SESSION TITLE: Asthma II
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM
PURPOSE: Chemical chaperones has been considered as an important regulator of bronchial asthma by improving airway inflammation, however the mechanism of chemical chaperones involved in insulin resistance remains not fully understood. In the present study, we investigated the effect of chemical chaperones (4-phenylbutyric acid, 4-PBA) on autophagy secondary to bronchial asthma in the lung tissues of OVA-OVA mice and in bronchial epithelial cell models, and clarified the intracellular events responsible for chemical chaperones-mediated effects.