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Allergy and Airway: Asthma I |

Association of BMI With Airways Hyper-Responsive to Methacholine

Karthik Vijayan, MD; Promish Shrestha, MD; Manuel Bautista, MD; Lawrence Goldstein, MD; Bhiputhi Neupane, MD
Author and Funding Information

Western Reserve Health Education, Youngstown, OH


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A13. doi:10.1016/j.chest.2016.02.015
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SESSION TITLE: Asthma I

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: Obesity increases the risk of asthma and contributes to a more difficult-to-control phenotype of the disease. In spite of the compelling evidence of association between asthma and obesity, relation between the BMI and increased airway/bronchial hyper-responsiveness (AHR/BHR) which is the basic physiological abnormality in asthma, has shown conflicting results. Provocative concentration of methacholine that reduces FEV1 by 20% (PC20) is a measure of AHR used in diagnosis of asthma. This study is aimed at exploring the relationship between BMI and PC20 in individuals suspected to have asthma, whose airways are hyper-responsive to methacholine.

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