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Allergy and Airway: Asthma I |

The Use of Omalizumab in Thetreatment of Nasal Polyps

Anna Yakinthou, PhD; Drosos Tsavlis, PhD; Ioannis Megas, MD
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Aristotle University of Thessaloniki, Thessaloniki, Greece


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A7. doi:10.1016/j.chest.2016.02.009
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SESSION TITLE: Asthma I

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: Allergic rhinitis and nasal polyps are associated with elevated serum immunoglobulin IgE levels. The allergens bind to IgE on the surface of basophils and mast cells, which releases histamine, leukotriens and others, following the symptoms of allergic rhinitis. Does the removal of free IgE by the anti-IgE antibody, omalizumab, improve the symptoms of allergic rhinitis and reduce nasal polyps? The answer to that question was the aim of this study.

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