Dr Fabbri has always linked the results of his experimental work to daily clinical practice. To further that interest, he served on the expert panels that produced guidelines initially on asthma (Global Initiative for Asthma [GINA]) and then COPD (Global Initiative for Chronic Obstructive Lung Disease [GOLD]). He organized, designed, and participated in several pivotal randomized trials that contributed evidence regarding the role of inhaled steroids, long-acting bronchodilators, combination therapy, and roflumilast in the management of asthma and/or COPD. Finally, over the last 10 years, he has focused his main interest on the concept of COPD as the pulmonary component of the chronic multimorbidity epidemic, which is becoming the most important health challenge of the century; he has contributed to the development of the field in terms of concepts, clinical studies, and educational activities. As President of the European Respiratory Society, Dr Fabbri co-organized a seminal research seminar on complex chronic comorbidities in Rome in 2007. The focus of his mission while serving for a year as President of the European Respiratory Society was on complex chronic comorbidities, developing and establishing new relationships between the respiratory community and other relevant medical and scientific communities (eg, cardiology, diabetes, oncology, internal medicine).