Sleep Disorders |

Increase in Heart Rate as a Surrogate EEG Arousal for Type 3 Ambulatory Recordings FREE TO VIEW

Serguei Marshansky, MS; Pierre Rompré, MS; Zeina Kaddaha, MD; Jobin Vincent, MD; Gilles Lavigne, PhD; Pierre Mayer, MD
Author and Funding Information

Universite de Montreal, Montreal, QC, Canada

Chest. 2015;148(4_MeetingAbstracts):1041A. doi:10.1378/chest.2281502
Text Size: A A A
Published online


SESSION TITLE: Sleep Disorders Posters I: Diagnosis

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 28, 2015 at 01:30 PM - 02:30 PM

PURPOSE: It is known that type 1 sleep recordings are costly and an alternative to EEG recording is needed. The aim of this study is to assess the heart rate (beat per min/bpm) cut-off that can be a sensitive and a specific surrogate to EEG arousals.

METHODS: 72 subjects suspected of obstructive sleep apnea (OSA) underwent one night sleep laboratory recording. The following respiratory outcomes were scored: 3% oxygen desaturation index (ODI), apnea-hypopnea index -AASM 2012- (AHI), respiratory disturbance index with EEG arousals (RDIe), and RDI with autonomic arousals (RDIa). Among the 72 subjects, data from 24 subjects were randomly chosen for preliminary analysis of cut-off assessments. A total of 2669 respiratory events were selected and 1762 hypopneas and 561 RERAs were included. Analyses performed for each event were: 1) EEG arousal and desaturation classification; 2) receiver operating characteristic (ROC) curves with EEG arousal as gold standard to assess different autonomic arousal cut-offs based on sensitivity and specificity.

RESULTS: Out of all the 1762 hypopneas, 714 were positive for EEG arousals and had no desaturations. Out of the 561 total RERAs, 371 RERAs had EEG arousals. A total of 1085 events were scored with EEG arousals. For a 5 bpm autonomic arousal cut-off, the sensitivity was 97.5% and the specificity 1.5%; with a cut-off of 10 bpm the sensitivity was 74.6% and the specificity 41.4%; with a cut-off of 15 bpm the sensitivity was 45.3% and the specificity 75.9%; and with a cut-off of 12 bpm the sensitivity was 61.8% and the specificity 57.2%.

CONCLUSIONS: An autonomic arousal cut-off value of 12 bpm identified 1020 over 1085 RDIe events.

CLINICAL IMPLICATIONS: The use of autonomic arousals is a good alternative to identify EEG arousals respiratory events.

DISCLOSURE: The following authors have nothing to disclose: Serguei Marshansky, Pierre Rompré, Zeina Kaddaha, Jobin Vincent, Gilles Lavigne, Pierre Mayer

No Product/Research Disclosure Information




Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
Vertebral subluxation in chiropractic practice.
Council on Chiropractic Practice | 9/4/3082
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543