SESSION TITLE: Interventional Pulmonology Posters II
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Wednesday, October 28, 2015 at 01:30 PM - 02:30 PM
PURPOSE: To determine through the SF-36 survey the burden of benign tracheal stenosis in the quality of life (QOL), and the impact of three different treatments in it. Secondary objective is to determine if age, sex and total treatment period influence the QOL.
METHODS: Prospective study from August to December 2014. We included patients with benign tracheal stenosis with Dumon stent, Montgomery T-Tubes or tracheostomy. Patients with stents or T-Tubes had adequate voice and breathing. Individuals with tracheostomy were included regardless of phonation. Other inclusion criteria were age between 18 and 65 years, willingness to participate in the study, fill the informed consent, and conditions to complete the survey. We excluded patients with acute or chronic disabling diseases. Patients were randomly selected to enroll in the study. SF-36 scores were analyzed as medians. Differences between groups were evaluated with Kruskal-Wallis, and corrected with Dunn's test. Linear regression model evaluated the influence of variables on the QOL scores. Alpha was set at 5%.
RESULTS: Ninety-three patients (62M) were included. Mean age was 38 + 14 years. Mean treatment time was 4.4 + 3.5 years. Treatment was tracheostomy (n=24; 26%), T-Tube (n=56; 60%) and Dumon stents (n=13; 14%). Median QOL in patients with tracheal stenosis is poor. Worst results were in role physical (RP) domain(12.5), bodily pain(22), and role emotional(33). Dumon stents scores were superior to other treatments in all domains. This difference was statistically significant only in the RP domain (p=0.04); Dumon vs tracheostomy, p=0.001; Dumon vs T-Tube, p=0.01. Results were compared with the SF-36 norm-based scores of the USA population. Dumon stents provided the best QOL, with 6 domains within mean values. RP and bodily pain were the most affected, but remained just 1 SD below the mean. Patients with tracheostomy had the worst QOL, with all domains below at least 1 SD from the mean. Treatment time significantly influenced QOL in the RP domain (f=46+3.38years; p=0.002; 95%CI 1.24-5.52).
CONCLUSIONS: QOL of patients with tracheal stenosis is poor. Differences exist according to the treatment. Dumon stents improve QOL and SF-36 scores are similar to the general population. Tracheostomy severely impairs QOL.
CLINICAL IMPLICATIONS: Knowledge of the differences in the QOL according to therapies for tracheal stenosis might help physicians decide between treatments. Differences detected in this study might facilitate sample size calculations in future studies.
DISCLOSURE: The following authors have nothing to disclose: Mauro Tamagno, Benoit Bibas, Paulo Cardoso, Helio Minamoto, Ricardo Terra, Paulo Pêgo-Fernandes
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