Obstructive Lung Diseases |

The Prevalence of Undiagnosed COPD at an Annual Health Screening in Mumbai, India FREE TO VIEW

Lancelot Pinto; Radhika Banka; Matthew Shorofsky; Jean Bourbeau, MD
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P D Hinduja Hospital & Medical Research Centre, Mumbai, India

Chest. 2015;148(4_MeetingAbstracts):703A. doi:10.1378/chest.2279391
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SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 28, 2015 at 01:30 PM - 02:30 PM

PURPOSE: 90% of global deaths from COPD occur in low- and middle-income nations. In India, the disease often remains undiagnosed due to a lack of awareness, and to the lack of universal access to spirometry. The purpose of the study was to determine the prevalence of undiagnosed COPD at a routine annual health screening at a tertiary care institute

METHODS: The P.D.Hinduja Hospital,Mumbai is a tertiary care center that caters to the population of the city. Between December 2014- February 2015, consecutive subjects undergoing spirometry as part of an annual health screening at P.D.Hinduja Hospital, Mumbai, India were included. Spirometry was conducted by trained technicians using the ATS criteria for acceptability and quality control. A postbronchodilator FEV1/FVC < 0.7 on spirometry was used as the reference standard for the diagnosis of COPD.

RESULTS: 326 subjects were enrolled and participated in the study. None of the subjects had a prior diagnosis of COPD. 38 subjects (12%) were diagnosed to have COPD on spirometry (No. of subjects in GOLD stages 1,2,3 were 16,19,3, respectively). Subjects with COPD did not differ significantly from those without the disease on sex or smoking status, but had a statistically significantly higher age (p=0.04), lower FEV1 (p<0.001) and CAT score (p=0.05).

CONCLUSIONS: There is a significant burden of undiagnosed COPD in the community. These individuals have lower lung function, and poorer quality of life than subjects without COPD. Non-smoking factors such as environmental pollution, biomass fuel exposure and sequelae of diseases such as tuberculosis need to be investigated as potential causative agents.

CLINICAL IMPLICATIONS: Individuals with COPD diagnosed at this screening had a poorer quality of life, suggesting that the routine use of spirometry for screening individuals with the disease might diagnose the disease at an early stage, leading to the possibility of improving the quality of life of such individuals, and altering the course of the disease. Acknowledgement: The study was funded by “Project Québec-Maharashtra, Relations internationales et de la Francophonie, Quebec”.

DISCLOSURE: The following authors have nothing to disclose: Lancelot Pinto, Radhika Banka, Matthew Shorofsky, Jean Bourbeau

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