Allergy and Airway |

Occurrence and Reoccurrence of Asthma-Related and All-Cause Emergency Department (ED)/Hospitalization Events FREE TO VIEW

Robert Suruki, DSc; Jonas Daugherty, PharmD; Nittaya Suppapanya; Frank Albers, MD
Author and Funding Information

GlaxoSmithKline, Worldwide Epidemiology, Research Triangle Park, NC

Chest. 2015;148(4_MeetingAbstracts):10A. doi:10.1378/chest.2277279
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SESSION TITLE: Allergy and Airway Posters

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 28, 2015 at 01:30 PM - 02:30 PM

PURPOSE: To describe the frequency of recurrent asthma-related and all-cause ED/hospitalization events following an index asthma-related ED/hospitalization event.

METHODS: This was a retrospective cohort study of asthma patients identified in a commercial claims database during 2010-2011. Eligible patients were required to have an asthma medical code (index date), an asthma medication within ± 3 months of the index date, and be aged ≥12 years. The 12-month period preceding the index date was examined to determine GINA treatment step and exacerbation history. The occurrence and reoccurrence of asthma-related and all-cause ED/hospitalizations was ascertained during the 12-month follow-up period. The reoccurrence of an asthma-related and all-cause ED/hospitalization event was examined during the 30-, 60-, and 90-day period following the first asthma-related ED/hospitalization (index event).

RESULTS: A total of 222,817 patients with asthma were identified; however, this analysis was limited to the 5,167 (2.3%) patients who experienced ≥1 asthma-related ED visit or hospitalization during the follow-up period. The mean (SD) age for this subset was 34.1 yrs (15.5) and 66.7% were female. Among the 5,167 patients, 9.2%, 12.5% and 15.5% experienced a reoccurrence of an asthma-related ED/hospitalization event during the 30-, 60-, and 90-days following the index event, respectively. Reoccurrence of an all-cause ED visit or hospitalization following an index event was seen in 22.6%, 37.0%, and 50.0% of subjects during the 30-, 60-, and 90-days following the index event, respectively. Although reoccurrence of asthma-related and all-cause ED/hospitalizations within 30-days of an index event during the study period increased with GINA step and history of exacerbation, it was highest among patients classified as GINA step 5 (14.9%) or with ≥2 exacerbations in the prior year (17.9%).

CONCLUSIONS: Nearly 10% of patients admitted to the ED or hospital for asthma experienced a second asthma-related ED/hospital admission during the subsequent 30-days. The risk for reoccurrence increased with greater GINA steps and a history of ≥2 exacerbations.

CLINICAL IMPLICATIONS: Proper medication and asthma management should be ensured for asthma patients admitted to the ED or hospital for asthma, particularly severe asthmatics given their increased risk of a recurrent ED/hospitalization event. (Funded by GSK; Study WEUSKOP7048)

DISCLOSURE: Robert Suruki: Employee: GlaxoSmithKline, Shareholder: GlaxoSmithKline Jonas Daugherty: Employee: GlaxoSmithKline, Shareholder: GlaxoSmithKline Nittaya Suppapanya: Employee: GlaxoSmithKline, Shareholder: GlaxoSmithKline Frank Albers: Employee: GlaxoSmithKline, Shareholder: GlaxoSmithKline

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