Obstructive Lung Diseases |

Factors Related to NIMV Failure in Hospitalized COPD Patients With Exacerbation FREE TO VIEW

Meltem Agca; Fatma Tokgoz; Dildar Yetis; Fatma Merve Tepetam; Aysun Misirlioglu; Hakan Gunen; Tulay Yarkin
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Sureyyapasa Chest Diseases and Chest Surgery Hospital/Istanbul, Istanbul, Turkey

Chest. 2015;148(4_MeetingAbstracts):737A. doi:10.1378/chest.2269667
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SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 28, 2015 at 01:30 PM - 02:30 PM

PURPOSE: Non-invasive mechanical ventilation (NIMV) is routinely used in exacerbations of COPD patients admitted with hypercapnia. In this study treatment results and factors affecting successful NIMV application in COPD patients in chest clinics were investigated.

METHODS: All COPD patients admitted to emergency clinics with acute hypercapnic respiratory failure between May 2010 and May 2012 were included in this study. After first application of NIMV in emergency clinics, patients were hospitalized and NIMV was continued in patient wards. Demographic properties, comorbidities, arterial blood gas findings on admission and follow-up, hematologic and biochemical findings were noted. Factors influencing success and failure (transfer to ICU or death) of NIMV application were investigated.

RESULTS: NIMV was successful in 377 patients (83.6%) and unsuccessful in 67 patients (16.4%). Factors affecting the failure were found as low albumin, high CRP, unresolved pH and PaCO2 levels 1 hour after application of NIMV, higher number of comorbidities, presence of any malignancy and low IPAP.

CONCLUSIONS: Our success rate is high in hospitalized patients having NIMV due to COPD exacerbation. In this study, we found multiple factors leading to failure of NIMV in COPD exacerbations. We think that clinicians should be careful about applying NIMV in COPD patients carrying these negative factors during exacerbation and should consider early admission to the ICU.

CLINICAL IMPLICATIONS: Clinicians can predict NIMV failure by using multipl parametres .

DISCLOSURE: The following authors have nothing to disclose: Meltem Agca, Fatma Tokgoz, Dildar Yetis, Fatma Merve Tepetam, Aysun Misirlioglu, Hakan Gunen, Tulay Yarkin




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