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Occupational and Environmental Lung Diseases |

Impact of an Ethanol Stove Intervention on Pulmonary Function in Pregnant Women Exposed to Household Air Pollution FREE TO VIEW

Vishan Dhamsania; Donee Alexander, PhD; Temitope Ibigbami; Adedayo Adepoju; Theodore Karrison, PhD; Oladosu Ojengbede, MBBS; C Olopade, MD
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University of Chicago, Chicago, IL


Chest. 2015;148(4_MeetingAbstracts):765A. doi:10.1378/chest.2267410
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Abstract

SESSION TITLE: Occupational and Environmental Lung Diseases Posters

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 28, 2015 at 01:30 PM - 02:30 PM

PURPOSE: To investigate the impact of replacing biomass or kerosene burning stoves with a bioethanol stove on pulmonary function and exposure-related pulmonary complaints in pregnant women in Ibadan, Nigeria

METHODS: We initiated a randomized controlled intervention trial of 300 pregnant women from Ibadan who cooked primarily with biomass or kerosene stoves. Participants were randomized at up to 18 weeks gestational age to one of two treatment groups: an intervention group with a CleanCook stove using bioethanol or a control group made up of kerosene and biomass users (depending upon which type of stove they were using at entry). During two separate 72-hour periods, personal exposure assessments of fine particulate matter less than 2.5 microns (PM2.5) and carbon monoxide (CO) were conducted during the second and third trimesters. Spirometry was performed prior to randomization, at 26 weeks of gestation and 6 weeks post-partum. Periodic surveys were administered to assess exposure-related complaints

RESULTS: Three hundred three pregnant women have been randomized into one of the three arms of the study; 154 women to bioethanol, 94 to kerosene and 55 to firewood. Spirometry was performed in 303 women at baseline, 206 at 26 weeks gestational age and 97 at 6 weeks post-partum. Two-sample t test comparing FVC, FEV1 and FEV1/FVC values at the two time points post-intervention did not yield significant differences between the intervention and control group. However, we observed significant reductions in exposure-related frequency of shortness of breath, fast breathing, headache and itchy eyes in the ethanol intervention group

CONCLUSIONS: Despite significant improvement in exposure-related pulmonary symptoms, no significant differences were observed in pulmonary function measures between the intervention group and controls. The lack of difference may be due to the relatively short interval between the baseline evaluation and the 6 weeks post partum evaluation, which is less than a year

CLINICAL IMPLICATIONS: An estimated one third of COPD deaths and a quarter of pneumonia deaths are attributable to household air pollution, which often results from the combustion of unsafe cooking fuels. This is one of the few, randomized controlled intervention trials using a clean fuel that aims to demonstrate the efficacy of a stove replacement program in improving pulmonary outcomes

DISCLOSURE: The following authors have nothing to disclose: Vishan Dhamsania, Donee Alexander, Temitope Ibigbami, Adedayo Adepoju, Theodore Karrison, Oladosu Ojengbede, C Olopade

No Product/Research Disclosure Information


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