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Obstructive Lung Diseases |

Chronic Obstructive Pulmonary Disease (COPD) Screening Using COPD Population Screener (COPD-PS) in Health Examinations for a General Population in Japan

Masayuki Nakayama, MD; Masashi Bando, MD; Hatsumi Ookubo, MD; Mio Nakayama, MD; Naoko Mato, MD; Hideaki Yamasawa, MD; Shuji Oishi, MD; Takefumi Saito, MD; Mikihiko Kawano, MD; Koichi Itoh, MD; Yukihiko Sugiyama, MD
Author and Funding Information

Jichi Medical University, Shimotsuke, Japan


Chest. 2015;148(4_MeetingAbstracts):687A. doi:10.1378/chest.2264909
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Abstract

SESSION TITLE: COPD Posters I

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 28, 2015 at 01:30 PM - 02:30 PM

PURPOSE: The purpose of this study was to evaluate the accuracy of COPD-PS as a screening tool for detecting COPD patients in a general population and also to evaluate the association between COPD questionnaires and lifestyle-related diseases.

METHODS: COPD screening using the COPD-PS and COPD assessment test (CAT) questionnaires was introduced in health examinations for the general population aged above 40 years in the city of Hitachiomiya, Japan, in 2014. All subjects participating in this health examination completed the two questionnaires, and the subjects who had a COPD-PS score of 4 or above were recommended to undergo spirometry at a medical institution. We retrospectively examined the proportion of COPD patients among the subjects who had COPD-PS scores of 4 or above; we determined the association among COPD-PS score, CAT score, and the results of health examination (body mass index [BMI], blood pressure, blood glucose level, and blood cholesterol level) in the screened subjects.

RESULTS: In all, 5830 subjects underwent this COPD screening, of whom 2044 (35.1%) had a COPD-PS score of 4 or above. Spirometry was performed on 541 participants, of whom 91 (16.8%) had air-flow limitation; 227 of the 541 individuals underwent post-bronchodilator spirometry, and 32 of the 227 subjects (14.1%) received a diagnosis of COPD. The clinical characteristics of those 32 patients were as follows: age 74.0±6.1 years; all male; COPD-PS score of 4.7±1.3; CAT score of 7.3±6.4; Global Initiative on Obstructive Lung Disease classification I/II/III/IV of 20/10/2/0, respectively; and smoking pack-years of 42.2±19.4. Hitherto, COPD had not been diagnosed in any of the patients, although most of them (84.4%) had regular contact with their primary care physician. With regard to the association between the two questionnaire scores and the results of health examination in the 5830 screened subjects, the COPD-PS score showed a significant positive correlation with CAT score (p<0.01). Furthermore, the COPD-PS score displayed a significant correlation with systolic blood pressure and blood glucose level (p<0.05); the CAT score had a significant correlation with BMI, systolic blood pressure, and blood cholesterol level (p<0.05).

CONCLUSIONS: COPD-PS is an uncomplicated, useful tool for detecting COPD; however, its positive predictive value is low. A high score for COPD-PS or CAT may be related to comorbidity in COPD.

CLINICAL IMPLICATIONS: COPD-PS alone is insufficient for COPD screening in the general population.

DISCLOSURE: The following authors have nothing to disclose: Masayuki Nakayama, Masashi Bando, Hatsumi Ookubo, Mio Nakayama, Naoko Mato, Hideaki Yamasawa, Shuji Oishi, Takefumi Saito, Mikihiko Kawano, Koichi Itoh, Yukihiko Sugiyama

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