Sleep Disorders |

Obstructive Sleep Apnea in Chronic Obstructive Pulmonary Disease - Overlap Syndrome in a Tertiary Care Center in Northern India FREE TO VIEW

Harshwant Grover, MBBS; Ashok Janmeja, MD; Deepak Aggarwal, MD
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Government Medical College and Hospital, Chandigarh, Chandigarh, India

Chest. 2015;148(4_MeetingAbstracts):1048A. doi:10.1378/chest.2263675
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SESSION TITLE: Sleep Disorders Posters I: Diagnosis

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 28, 2015 at 01:30 PM - 02:30 PM

PURPOSE: Obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) are quite common diseases. The coexistence of OSA and COPD is termed ‘overlap syndrome’. Adequate data on the burden of ‘overlap syndrome’ in the Indian scenario is not available so far, hence the burden of this dual disease entity needs further evaluatuion especially from India. Therefore the present study has been planned to generate some useful data on the association of COPD and OSA in our country.

METHODS: This was a cross sectional observational study performed in a tertiary care hospital. Based on clinical symptoms and diagnostic criteria laid down by the Global Initiative for Chronic Obstructive Lung Disease (GOLD), 50 random patients of COPD were enrolled. After due consent, patients underwent overnight polysomnography for evaluation of sleep apnea using the compumedics E-series-44 channel polysomnography system. All subjects were categorized into 3 groups of mild, moderate and severe COPD based on GOLD guidelines and the presence of OSA in these groups was evaluated.

RESULTS: Of the 50 subjects ( 39 males, 11 females ) who completed the study, the mean age was 52 ± 11 years, height 163.3 ± 9 cms and body mass index was 29.3±7 kg/m2. In our study, 14 % of COPD patients were found to be suffering from OSA on the basis of overnight polysomnography. COPD patients were further divided into 3 groups: Mild COPD [FEV1≥ 80 %], moderate COPD [50%≤ FEV1< 80%], Severe COPD 30% ≤FEV1< 50 %]. 9% of the patients in the mild COPD group (n=22) suffered from OSA. 10% of the patients in moderate COPD group (n=20) suffered from OSA and 37.5 % of the patients in severe COPD group(n=8) suffered from OSA.

CONCLUSIONS: High prevalence of OSA in COPD patients points towards strong association between OSA and COPD. There is direct correlation between OSA and increasing severity of COPD stages.

CLINICAL IMPLICATIONS: Screening COPD patients for OSA and subsequent treatment of both these conditions may decrease the morbidity. The high prevalence of OSA in severe stage COPD warrants screening of all severe stage COPD patients for OSA.

DISCLOSURE: The following authors have nothing to disclose: Harshwant Grover, Ashok Janmeja, Deepak Aggarwal

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