Lung Cancer |

A Rare Cause of Endobronchial Metastasis: Malignant Melanoma FREE TO VIEW

Akin Kaya, MD; Aydin Ciledag, MD; Ebru Karacay, MD; Aslihan Kaya, MD; Nazan Ciledag, MD; Demet Karnak, MD; Gungor Utkan, MD
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Ankara University Faculty of Medicine, Ankara Turkey, Ankara, Turkey

Chest. 2015;148(4_MeetingAbstracts):534A. doi:10.1378/chest.2224300
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SESSION TITLE: Lung Cancer Case Report Posters II

SESSION TYPE: Affiliate Case Report Poster

PRESENTED ON: Tuesday, October 27, 2015 at 01:30 PM - 02:30 PM

INTRODUCTION: Thorax is a common site of metastasis in patients with malignant melonama and usually observed as parenchymal nodules (rarely miliary form) and hilar/mediastinal lymphadenopathy. However, endobronchial metastasis is uncommon.

CASE PRESENTATION: A 44 years-old male was admitted with hemoptysis. He had an history of operation due to malignant melanoma originated from a nevus in the left leg. Localized rhonchi was heard at the left side of hemithorax. A chest X-ray revealed left hilar enlargement and a thorax computed tomography showed left hilar mass. Bronchoscopy was performed and a pigmented endobronchial mass that fully obstructing lingula was observed. Endobronchial biopsy was taken and the pathological examination revealed malignant melanoma metastasis. During follow-up, hemoptysis persisted and therapeutic bronchoscopy was performed. An active bleeding was observed and hemorrhagic tumor was coagulated by Argon plasma coagulation (APC). Hemoptysis did not recur after this procedure.

DISCUSSION: Melanomas are derived from melanocytes, which originate in the neural crest and are widely distributed through the skin and other tissues. Primary melanoma most commonly arises from the skin; however, it can also develop in other areas, including the eye and mucosae (1). Although, the thorax is one of the most common site of disease relapse in patients with malignant melanoma, endobronchial metastasis from melanoma is uncommon and not well-documented (2). Also, there is little data about therapuetic approach for hemoptyisis secondary to endobronchial metastasis.

CONCLUSIONS: The patient was presented because of extremely rare occurence of endobronchial metastasis of malignant melanoma and successful outcome of APC in such cases.

Reference #1: Patnana M, Bronstein Y, Szklaruk J, et al. Multimethod imaging, staging, and spectrum of manifestations of metastatic melanoma. Clin Radiol 2011;66:224-36

Reference #2: Chung CY, Likhari GS, Zarrin-Khameh N, Nachiappan AC. Hyperdense endobronchial mass-a rare manifestation of metastatic melanoma. J Clin Imaging Sci 2014;25:4-7.

DISCLOSURE: The following authors have nothing to disclose: Akin Kaya, Aydin Ciledag, Ebru Karacay, Aslihan Kaya, Nazan Ciledag, Demet Karnak, Gungor Utkan

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