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Use of Clinical Predictors on Diagnosis of OSAS in Patients With Chronic Obstructive Pulmonary Disease, Asthma, and Cardiovascular Diseases FREE TO VIEW

Hamdy Mohammadien, MD; Suzan Salama, MD; Azza Ahmad, MD
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Sohag University-Sohag Faculty of Medicine, Sohag-Elmaragha-Nagecc Elhakim, Egypt

Chest. 2015;148(4_MeetingAbstracts):1040A. doi:10.1378/chest.2215664
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SESSION TITLE: Sleep Disorders Poster Discussions

SESSION TYPE: Original Investigation Poster Discussion

PRESENTED ON: Wednesday, October 28, 2015 at 07:30 AM - 08:30 AM

PURPOSE: The aim of this study was to identify predictors for the diagnosis of OSAS in patients with COPD, asthma and CVD.

METHODS: This study included 180 patients, 60 COPD, 60 asthmatics and 60 patients with CVD without previously diagnosed OSA. We evaluated a questionnaire on the clinical predictors of the OSAS and anthropometric, arterial blood gases & pul.F parameters.

RESULTS: The multivariable logistic regression revealed that Snoring(OR=4.8,0.009) & nocturia (OR=5.9)are a predictors for high ESS more than 10 in cardiac patients, uncontrolled DM and hypertension in asthmatic patients and uncontrolled hypertension among all patients. D.M, Uncontrolled DM & hypertension were significantly related to high risk STOP Bang in the COPD, uncontrolled hypertension in all patients, & nocturia, uncontrolled DM in asthmatic. Nocturia, poor memory and D.M. can be considered as a strong predictors for high risk Berlines questionnaire in COPD and asthmatic patients. Headache & hypertension in all the patients. Nocturia (OR=8.2, 6.1 & 9.5) can be considered strong predictor for high risk ASA Checklist among all the patients as well as headache in the cardiac patients while poor memory, hypertension and D.M (OR=3.4, 2.2 &5.8) in the COPD patients. BMI, neck & waist circumference cannot be used as a possible predictors of high risk for OSAS by any of the used questionnaires in the cardiac patients. While in COPD patients BMI, & neck circumference (OR=8.1,3.7&5.8, 2.4 ) are a strong predictors for high risk Berlines & ASA Checklist, also in asthmatics waist circumference (OR=1.04) can be used as predictor for high risk for OSAS. PaO2 at 12 am and SaO2% at 12 am can be considered as predictors for ESS in all patients. PaCO2, PaO2 and SaO2% at 12 am could be used as predictors for high risk patients for OSAS using STOP Bang, Berlines and ASA Checklist. FEV1 can be used as a predictor for high risk for OSAS using high ESS score & ASA Checklist (OR=1.1 & 1.1) in COPD not in asthmatics. Most patients with high ESS score, Berlines questionnaire and ASA Checklist were uncontrolled asthmatic patients.

CONCLUSIONS: We found that many predictors along with the used questionnaires can be utilized to predict the probability of having OSAS. These parameters include nocturia, hypertension, uncontrolled hypertension, DM, uncontrolled DM, BMI, neck circumference and PaO2 at 12 am.

CLINICAL IMPLICATIONS: These anatomical or clinical variable can be utilized to predict patients with the probabiltity of having OSAS before performing polysommonography

DISCLOSURE: The following authors have nothing to disclose: Hamdy Mohammadien, Suzan Salama, Azza Ahmad

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