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Chest Imaging and Pathology for Clinicians |

A 72-Year-Old Woman With Previous Pulmonary Metastasis and New Peripheral NoduleWoman With a New Pulmonary Peripheral Nodule

Giovanni Maria Comacchio, MD; Chiara Giraudo, MD; Nazarena Nannini, MD; Alessandro Rebusso, MD; Roberta Polverosi, MD; Federico Rea, MD; Fiorella Calabrese, MD
Author and Funding Information

From the Division of Thoracic Surgery (Drs Comacchio, Rebusso, and Rea), and the Pathological Anatomy Section (Drs Nannini and Calabrese), Department of Cardiothoracic and Vascular Sciences, and the Radiology Section (Dr Giraudo), Department of Medicine, University of Padova, Padova; and the Department of Radiology (Dr Polverosi), Hospital of S. Donà di Piave, Venice, Italy.

CORRESPONDENCE TO: Fiorella Calabrese, MD, Department of Cardiothoracic and Vascular Sciences, Pathological Anatomy Section, University of Padova Medical School, via A.Gabelli 61, 35121 Padova, Italy; e-mail: fiorella.calabrese@unipd.it


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2015;148(2):e42-e47. doi:10.1378/chest.14-2598
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A 72-year-old female nonsmoker was admitted to our Thoracic Surgery Unit in 2013 because of a lesion detected on chest CT scan during oncologic follow-up. Her medical history was significant for the development of a single pulmonary metastasis discovered 1 year after sigmoidectomy for colic adenocarcinoma. At that time, the patient was treated with six cycles of neoadjuvant chemotherapy followed by left lower lobectomy. Histologic examination demonstrated a pulmonary metastasis of colic adenocarcinoma with diffuse necrotic areas. The patient underwent subsequent adjuvant chemotherapy with capecitabine and was followed annually with biohumoral oncologic screening (carcinoembryonic antigen, carbohydrate antigen 19-9), chest-abdomen CT scan, and colonoscopy.

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