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A 50-Year-Old Man Presenting With Cough and an Endobronchial Lesion After Initiation of Highly Active Antiretroviral TherapyCough and Endobronchial Lesion After Therapy

Matthew A. McCullough, MD; Chisa Aoyama, MD; Nader Kamangar, MD, FCCP
Author and Funding Information

From the Department of Medicine (Dr McCullough), Department of Pathology (Dr Aoyama), and Division of Pulmonary and Critical Care Medicine, Department of Medicine (Dr Kamangar), Olive View-UCLA Medical Center, Sylmar, CA.

CORRESPONDENCE TO: Nader Kamangar, MD, FCCP, Division of Pulmonary and Critical Care Medicine, Olive View-UCLA Medical Center, David Geffen School of Medicine at UCLA, 14445 Olive View Dr, Room 2B-182, Sylmar, CA 91342; e-mail: kamangar@ucla.edu


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2015;148(1):e14-e17. doi:10.1378/chest.14-2298
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A 50-year-old black man with newly diagnosed HIV/AIDS, genital herpes, and latent syphilis presented with a nonproductive cough. The patient received a diagnosis of HIV and started highly active antiretroviral therapy (HAART) with emtricitabine/tenofovir disoproxil fumarate, darunavir, and ritonavir 2 months prior to presentation. CD4+ count was 1/μL and viral load was 538,884 copies/mL prior to initiation of HAART. The patient endorsed compliance with all medications since diagnosis. The patient had a persistent, dry cough at time of HIV diagnosis that had acutely worsened during the 2 weeks leading to admission. He denied fevers, chills, hemoptysis, or dyspnea but did endorse drenching night sweats.

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