When told 10 years ago that some medical centers were experiencing overdiagnosis, I laughed, but I do not laugh anymore. The epidemic of overdiagnosis8 is such that when I am called about HIT suspicion, only one in three patients may actually have it. It is easy to appreciate the factors underlying this epidemic. Physicians have become attuned to the problem, whether from publications, lectures, experiencing a catastrophe or two in their own patients, or even from involvement in lawsuits (there have been plenty); they are imbued with the need not to miss this diagnosis. The availability of serologic tests for HIT (just check a box) and the high “false-positive” rates of the tests have fed overdiagnosis. Face it, poorly informed and/or lazy physicians would like to believe a test would give them definitive results, rather than that they have to learn about disease characteristics, about when suspicion is appropriate, and about properly interpreting test results. Overdiagnosis is further fueled by the lack of appreciation of the serious negative ramifications this diagnosis conveys.