Here, we have considered mandatory vaccination at school entry from an ethical perspective. In our ethical analysis we have taken into account values such as avoiding harm, autonomy, social justice, and health maximization.5 We are convinced that it is essential to use as little compulsion as possible for successful and justifiable immunization programs.6 Allowing school enrollment only if the child is immunized is a form of compulsion. It is de facto compulsion for many parents, because private alternatives to school like home schooling might be difficult to afford or to accomplish for many parents. Pragmatically, many parents need supervision of their children while they go to work. Thus, not allowing children to attend school is, for many parents, no option.