Ruan et al1 included five prospective studies in the meta-analysis. They compared 30-day mortality and 30-day complicated clinical events (CCEs) in patients with acute PE demonstrating elevated H-FABP levels (above cutoff) with patients with normal H-FABP levels (below cutoff). Of the five studies used, however, two, by Dellas et al4 and Puls et al,5 had an overlap of 73 patients, which alters the OR for final end points. The authors reported a higher OR of 40.78 (95% CI, 11.87-140.01; I2 = 4%) for the 30-day mortality rate and an OR of 32.71 (95% CI, 11.98-82.97; I2 = 21%) for the 30-day CCE. If we exclude the study by Puls et al5 and include only the study by Dellas et al4 (due to higher patient volume), then the OR becomes 31.38 (95% CI, 8.32-118.39; I2 = 23%) for the 30-day mortality and 25.93 (95% CI, 10.72-62.70; I2 = 28%) for the 30-day CCE.