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Chest Imaging and Pathology for Clinicians |

A 40-Year-Old Woman With Multiple Pulmonary Nodules40-Year-Old Woman With Multiple Pulmonary Nodules

Kamonpun Ussavarungsi, MD; Andras Khoor, MD, PhD; Howard I. Jolles, MD; Isabel Mira-Avendano, MD
Author and Funding Information

From Pulmonary and Critical Care Medicine (Drs Ussavarungsi and Mira-Avendano), Laboratory Medicine and Pathology (Dr Khoor), and Diagnostic Radiology (Dr Jolles), Mayo Clinic, Jacksonville, FL.

CORRESPONDENCE TO: Kamonpun Ussavarungsi, MD, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224; e-mail: Ussavarungsi.Kamonpun@mayo.edu


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2014;146(6):e198-e203. doi:10.1378/chest.14-0796
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A 40-year-old woman (a nonsmoker) with history of idiopathic thrombocytopenic purpura and a platelet count > 90,000 cells/μL without specific medication was referred to pulmonary clinic for evaluation of multiple pulmonary nodules. The patient presented to an outside hospital with fatigue, lack of energy, and dyspnea on exertion for 2 years. She denied fever, cough, chest pain, or weight loss. An initial chest radiograph showed bilateral multiple pulmonary nodules. A chest CT scan revealed multiple nodular lesions, varying in size, in all lobes of both lungs. There was no mediastinal lymphadenopathy or pleural effusion. There was no significant hypermetabolic activity on a subsequent fluorodeoxyglucose PET scan/CT scan, and there had been no significant change. She underwent CT scan-guided percutaneous transthoracic biopsy and bronchoscopy with transbronchial biopsies, all of which were inconclusive. An open lung biopsy was considered.

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