Allergy and Airway |

Body Mass Index and Outcomes in Patients Diagnosed With Chronic Obstructive Pulmonary Disease FREE TO VIEW

Prangthip Charoenpong, MD
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Advocate Illinois Masonic Medical Center, Chicago, IL

Chest. 2014;146(4_MeetingAbstracts):40A. doi:10.1378/chest.1995278
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SESSION TITLE: COPD Diagnosis and Evaluation Posters II

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 29, 2014 at 01:30 PM - 02:30 PM

PURPOSE: Recent studies have shown that lower body mass index (BMI) is associated with higher mortality rate in many conditions such as in ICU patients, pneumonia patients, so called, obesity paradox. We aimed to examine the association between BMI and mortality in acute COPD exarcerbation (AECOPD) patients.

METHODS: This study is a retrospective review of 136 patients hospitalized for AECOPD from January 1, 2011 to December 31, 2011. The demographic data, clinical manifestation, laboratory findings, and treatment were collected from medical record. The length of hospital stay (LOS) and 1-year mortality rate (MR) were compared between obese group and non-obese group.

RESULTS: From 136 patients (mean 69.7±11.7 years old, 47.1 % male), 80 patients (58.8%) were categorized into obese group defined by BMI > 25, whereas 56 patients (47.2) were in non-obese group. When compared between 2 groups, the 1-year MR were 12.5% and 30.4% (p=0.01), LOS were indifferent, 3.43 days and 3.8 days (p=0.56). The number of total visit are 2.3 and 1 (p=0.047) in obese and non-obese group respectively.

CONCLUSIONS: Multiple studies have revealed the association between BMI and outcome in patients in many populations. In our study, we found that being overweight or obese is associated with surviving at 3 months. The exact mechanism is unknown but many hypotheses have been proposed. This study suggests that obesity is associated with better survival rate of COPD patients (lower 1-year MR), although the LOS is nonstatistical significant and the number of revisit is higher in obese COPD patients.

CLINICAL IMPLICATIONS: Obesity paradox in COPD patients in term of mortality rate is consistent with previous studies. Obesity does not effect length of hospital stay and number of revisit.

DISCLOSURE: The following authors have nothing to disclose: Prangthip Charoenpong

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