Pulmonary Rehabilitation |

Respiratory Muscle Pressures in COPD Patients Stratified in Groups of Risk Acording to GOLD 2013 Classification FREE TO VIEW

Alina Croitoru; Daniela Jipa; Diana Ionita, MD; Stefan Dumitrache-Rujinski, MD; Paraschiva Postolache, MD; Claudia Toma, MD; Ionela Belaconi; Miron Bogdan, MD
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National Institute of Pneumology, Bucharest, Romania

Chest. 2014;146(4_MeetingAbstracts):811A. doi:10.1378/chest.1994304
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SESSION TITLE: Physiology/PFTs/Rehabilitation Posters

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 29, 2014 at 01:30 PM - 02:30 PM

PURPOSE: Respiratory muscle impairment in COPD patients may lead to dyspnoea and decreased quality of life.The aim of the study was to evaluate the respiratory muscle pressures in COPD patients.

METHODS: In 50 stable COPD patients (stratified in groups of risk acording to GOLD 2013 classification) we evaluated: respiratory muscle strength measurements (maximal inspiratory pressure: MIP, maximal expiratory pressure: MEP), spirometry (FEV1), modified Medical Research Council (mMRC) dyspnea scale, COPD Assessment Test (CAT).

RESULTS: Group A and C totalized 3 patients (1 and respectively 2), not enough to perform a statistical analysis. In group B: 18 patients, mean age 66.78±11 years, mean FEV1: 1.66±0.4 L (62.2±10% predicted). Mean MIP value 58.5±24.8 cm H20. Mean MEP value109.72±48 cm H20. In group D: 29 patients, mean age 60.52±10 years, mean FEV1: 1.11±0.2 L(36.16±7% predicted). Mean MIP value 70.9±20 cm H20. Mean MEP value 127.83±32.2 cm H20.

CONCLUSIONS: Surprisingly, the highest respiratory muscle pressures values ​​were found in group D (symptomatic patients with frequent exacerbations), probably due to the fact that our patients had a body mass index in the normal range. Further studies are needed on a larger number of COPD patients, covering all groups of risk according to COPD - GOLD 2013 classification, in order to verify this findings.

CLINICAL IMPLICATIONS: The etiology of respiratory muscle impairment in COPD patients is multifactorial, and more parameters need to be evaluated in order to asses the condition of the respiratory muscles.

DISCLOSURE: The following authors have nothing to disclose: Alina Croitoru, Daniela Jipa, Diana Ionita, Stefan Dumitrache-Rujinski, Paraschiva Postolache, Claudia Toma, Ionela Belaconi, Miron Bogdan

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