SESSION TITLE: Physiology/PFTs/Rehabilitation Posters
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Wednesday, October 29, 2014 at 01:30 PM - 02:30 PM
PURPOSE: Respiratory muscle impairment in COPD patients may lead to dyspnoea and decreased quality of life.The aim of the study was to evaluate the respiratory muscle pressures in COPD patients.
METHODS: In 50 stable COPD patients (stratified in groups of risk acording to GOLD 2013 classification) we evaluated: respiratory muscle strength measurements (maximal inspiratory pressure: MIP, maximal expiratory pressure: MEP), spirometry (FEV1), modified Medical Research Council (mMRC) dyspnea scale, COPD Assessment Test (CAT).
RESULTS: Group A and C totalized 3 patients (1 and respectively 2), not enough to perform a statistical analysis. In group B: 18 patients, mean age 66.78±11 years, mean FEV1: 1.66±0.4 L (62.2±10% predicted). Mean MIP value 58.5±24.8 cm H20. Mean MEP value109.72±48 cm H20. In group D: 29 patients, mean age 60.52±10 years, mean FEV1: 1.11±0.2 L(36.16±7% predicted). Mean MIP value 70.9±20 cm H20. Mean MEP value 127.83±32.2 cm H20.
CONCLUSIONS: Surprisingly, the highest respiratory muscle pressures values were found in group D (symptomatic patients with frequent exacerbations), probably due to the fact that our patients had a body mass index in the normal range. Further studies are needed on a larger number of COPD patients, covering all groups of risk according to COPD - GOLD 2013 classification, in order to verify this findings.
CLINICAL IMPLICATIONS: The etiology of respiratory muscle impairment in COPD patients is multifactorial, and more parameters need to be evaluated in order to asses the condition of the respiratory muscles.
DISCLOSURE: The following authors have nothing to disclose: Alina Croitoru, Daniela Jipa, Diana Ionita, Stefan Dumitrache-Rujinski, Paraschiva Postolache, Claudia Toma, Ionela Belaconi, Miron Bogdan
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