SESSION TITLE: Physiology/PFTs/Rehabilitation
SESSION TYPE: Original Investigation Slide
PRESENTED ON: Tuesday, October 28, 2014 at 08:45 AM - 10:00 AM
PURPOSE: The purpose of this study is to determine the benefits of pulmonary rehabilitation on patients with non-COPD lung diseases in terms of dyspnea, quality of life, depression and functional exercise capacity.
METHODS: Retrospective database review using the APPROACH DATABASE in the pulmonary rehabilitation department of a community hospital was done. All patients who participated and completed the pulmonary rehabilitation program from 1998 - 2013 were included. Non-COPD patients included those with lung disease other than COPD as confirmed by pulmonary function test, imaging studies (chest X-ray, chest CT scan), lung biopsy and as diagnosed by a pulmonologist. These included those with asthma, bronchiectasis, interstitial lung diseases, pulmonary fibrosis, asbestosis, sarcoidosis, kyphoscoliosis, chest wall deformities, morbid obesity, pulmonary hypertension and surgery including volume reduction surgery, transplantation or partial lung removal for cancer or other illnesses. Outcomes were compared at baseline and end of rehabilitation program using the following: 1. Shortness of breath using UCSD Medical Center Shortness of Breath Questionnaire. 2. Health-related quality of life using Ferrans and Powers Quality of Life Index Pulmonary Version-III Questionnaire. 3. Depression using the Zung Depression Screening tool. 4. Functional exercise capacity using the six minute walk test (6MWT).
RESULTS: There were a total of 1280 patients who were enrolled in pulmonary rehabilitation. 342 patients were diagnosed with pulmonary conditions other than COPD. Paired t-test was used to compare outcomes. The distance travelled during the 6 MWT at the end of pulmonary rehabilitation was statistically longer prior to initiation of pulmonary rehabilitation (1069.2 ± 319.3 vs. 884.2 ± 297.7; P value <0.0001). There was also a significant improvement in quality of life index at the end of pulmonary rehabilitation (18.08 ± 2.82 vs. 17.33 ± 2.36, P value <0.0074). The patients had significantly less shortness of breath at the end of their rehabilitation (41.06 ± 21.5 vs. 48.6 ± 22.8, P value <0.008) and also noted improvement in their mood as assessed by the Zung depression screening tool (46.5 ± 10.3 vs. 51.0 ± 11.5, P value <0.0001).
CONCLUSIONS: Pulmonary Rehabilitation improves exercise capacity, quality of life, mood and dyspnea in non-COPD patients.
CLINICAL IMPLICATIONS: These important findings necessitate further study in a large, prospective trial to explore these possible benefits.
DISCLOSURE: The following authors have nothing to disclose: Siddharth Dugar, Ria Calata, Mena Megellie, John Paul Rosales, Kala Davis-McDonald
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