Sleep Disorders |

The Burden of Cardiovascular Morbidities in Veteran With OSA FREE TO VIEW

Bashar Albarghuthy; Vivek Jain; Richard Amdur; Steven Singh
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The George Washington University, Washington, DC

Chest. 2014;146(4_MeetingAbstracts):950A. doi:10.1378/chest.1989762
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SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 29, 2014 at 01:30 PM - 02:30 PM

PURPOSE: Obstructive Sleep Apnea (OSA) is associated with increased risk of cardiovascular comorbidities. We aimed to examine the burden of cardiovascular comorbidities and/or mortality in veterans with OSA.

METHODS: We conducted a retrospective analysis of veteran’s charts with OSA at the Veterans Affairs Hospital in Washington DC from January 1st, 2001 to December 31st, 2010 using the Electronic Health Records. We collected data about OSA diagnosis dates, patient’s demographics, BMI, mortality and comorbidities, including DM, HTN, Hyperlipidemia (HLP), CAD, CHF, Atrial fibrillation (AF) and CVA/ TIA. The institutional review board approved the study.

RESULTS: We identified 4327 consecutive patients with OSA diagnosed during the time frame January 1st, 2001 to December 31st, 2010. The mean age was 55.31 years [SD 12.20], the mean BMI 34.2 Kg/m2 (SD 6.82), blacks 49.8% (2157 patinets), whites 31.2% (1350 patinets) and the majority were males (91.77%). They had a high prevalence of different cardiovascular comorbidities and risk factors, most commonly HTN (58.7%), followed by HLP (49.8%), DM (28%), CAD (10.4%), CHF (5.1%), AF (4.2%), CVA/TIA (2.3%) and had a mortality of 3.7% during 10 years of follow up. Whites had a higher prevalence of AF and CAD compared to blacks (7.6% and 16.5% Vz 3.5% and 8.2%, consecutively, p< 0.0001), however blacks had a higher prevalence of HTN and DM than whites (67.6% and 33.7% Vz 54.6% and 24.7%, consecutively, p<0.0001).

CONCLUSIONS: Veterans with OSA have a high burden of cardiovascular risk factors and morbidities. Racial differences in these co morbidities warrant further research.

CLINICAL IMPLICATIONS: OSA is a common disease. CPAP is the best treatment modality, however many patients can't tolerate it. More research is needed to find other treatment modalities as OSA is associated with different cardiovascular risk factors and comorbidities.

DISCLOSURE: The following authors have nothing to disclose: Bashar Albarghuthy, Vivek Jain, Richard Amdur, Steven Singh

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