Imaging |

A Web-Accessible Computer Application ("App") for Temperature Adjustment of Arterial Blood Gas (ABG) Parameters During Therapeutic Hypothermia FREE TO VIEW

Robert Demers; Javier Morquecho; John Trudeau; Wayne Wallace
Author and Funding Information

Southern California Permanente Medical Group, Pasadena, CA

Chest. 2014;146(4_MeetingAbstracts):573A. doi:10.1378/chest.1989686
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SESSION TITLE: Diagnostic Procedures and Interventions Posters

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 29, 2014 at 01:30 PM - 02:30 PM

PURPOSE: Some brands/models of arterial blood gas (ABG) analyzers incorporate algorithms to determine arterial pH (pHa), arterial carbon dioxide tension (paCO2), and arterial oxygen tension (paO2) at body temperatures which vary from the normal, 37° Centigrade. We’ve developed a stand-alone, web-accessible computer application (“app”) to perform this task whenever in vivo temperatures are substantially lower than 37°, such as occurs during therapeutic hypothermia.

METHODS: We modified a standard equation to calculate the temperature-adjusted pHa1. In order to derive an expression for temperature-adjusted paCO2 and paO2 values, we empirically derived equations which would yield values for those parameters which agreed with an array of temperature-adjusted figures published in a classic text2. The equations were then imported into standard spreadsheet software (Numbers®, Apple Inc., Cupertino, CA). The user keys in the pHa, paCO2, and paO2 values referable to 37° C, as well as entering the hypothermic temperature of interest. The spreadsheet maps the results of its‘ calculations to corresponding fields within the app, displaying both the unadjusted and the temperature-adjusted values.

RESULTS: The app’s data were compared to corresponding figures determined by Shapiro et al, and found to be identical throughout the temperature range 20° C through 39° C.

CONCLUSIONS: The app resides at this Universal Resource Locator (URL): http://www.clinimapp.com/temperature-adjustment It can be accessed, free of charge, using any desktop/laptop/tablet/handheld computer or smartPhone,which incorporates browser software.

CLINICAL IMPLICATIONS: The app exhibits the following advantages, as compared to ABG analyzers’ integral algorithms: 1) it can be applied both retrospectively and prospectively; 2) it can be employed with any brand or model of ABG analyzer; and 3) it’s free, as opposed to the cost ($1,600+) of proprietary systems. References: 1. ABL 800 FLEX Reference Manual, publication 201206, Edition J, Equation 1, Page 6-28, Radiometer Medical ApS, Westlake, OH 2. Shapiro BA, Harrison RA, Walton JR. Clinical Application of Blood Gases, 3rd Edition, Chicago, IL, Year Book Medical Publishers, 1977, Table 49.1

DISCLOSURE: The following authors have nothing to disclose: Robert Demers, Javier Morquecho, John Trudeau, Wayne Wallace

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