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Pulmonary Rehabilitation |

Correlates of Abnormal Lung Functions in Type 2 Diabetes in Lagos, Nigeria FREE TO VIEW

Olayinka Adeyeye, MPH; Anthonia Ogbera, MPH
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Medicine, Lagos State University College of Medicine, Lagos, Nigeria


Chest. 2014;146(4_MeetingAbstracts):806A. doi:10.1378/chest.1984995
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Abstract

SESSION TITLE: Physiology/PFTs/Rehabilitation Posters

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 29, 2014 at 01:30 PM - 02:30 PM

PURPOSE: Diabetes mellitus is associated with pulmonary complications, the magnitude of which is frequently under reported. The increasing prevalence of DM necessitates the need to further characterise its effects on the lung as a probable target organ. This study was conceived to determine the ventilatory pattern of patients with diabetes as well as the effect of body mass index, age, glycosylated haemoglobin, duration of diabetes and blood glucose levels on the pulmonary functions.

METHODS: Two hundred consecutive patients with Diabetes mellitus who consented and met inclusion criteria were recruited. The pulmonary function test was carried out using the spirotrac intuitive version V and according to standard guidelines. Statistic tests employed include Students’s t test, correlation coefficient analysis and binary logistic regression.

RESULTS: The ages of the Study participants ranged from 19-90 years, with a mean of 59.6±11.30 years. The mean BMI, FBS, Systolic and DBP were 28.4 ±6.00, 149.7±78 .2 mg/dl, 135.4±21.5 mmHg, and 79.4±12 mmHg respectively. Well over half 114-(57%) of the Diabetics had abnormal ventilatory pattern and the prevalent ventilatory defect noted was Restrictive ventilatory defect which occurred in 76(67%) of the diabetics. We noted significant associations between Age (r= -28, p=000), duration of DM (r=-15, p=034) and lung function. A possible predictor of abnormal pulmonary function test was the presence of hypertension (Odds ratio=0.39, p= 0.009).

CONCLUSIONS: We have reported that Restrictive lung function defect is common among patients with diabetes mellitus and non modifiable clinical parameters are associated with abnormal lung function in this group of patients

CLINICAL IMPLICATIONS: The lung is also an important target organ for damage in Diabetes Mellitus. careful attention to Diabetes control and regular screening for it anongst the patient may improve overall outcome in individuals with Type 2 dm

DISCLOSURE: The following authors have nothing to disclose: Olayinka Adeyeye, Anthonia Ogbera

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