0
Allergy and Airway |

Spirometric Response to Bronchial Thermoplasty in Patients With Severe Asthma

Andrew Porter; Brent Brown
Author and Funding Information

University of Oklahoma, Oklahoma City, OK


Chest. 2014;146(4_MeetingAbstracts):10A. doi:10.1378/chest.1971101
Text Size: A A A
Published online

Abstract

SESSION TITLE: Asthma Posters I

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 29, 2014 at 01:30 PM - 02:30 PM

PURPOSE: Bronchial thermoplasty is an FDA approved procedure for the treatment of severe asthma. Previous studies have not documented an improvement in FEV1 or FVC after thermoplasty, although these studies did not enroll patients with moderate to severe obstruction on spirometry. We sought to determine the effect of bronchial thermoplasty on pulmonary function in patients with documented obstruction on spirometry.

METHODS: Baseline spirometric data from severe asthma patients who underwent bronchial thermoplasty were compared to data obtained one to three months after the procedure.

RESULTS: All patients had a preprocedure FEV1 of less than 60%. In all five patients, FEV1 and FVC improved after the procedure. Mean FEV1 preprocedure was 52% (range 46-60%) predicted, which improved to 67% (range 54-77%) predicted (p=0.02). Mean FVC preprocedure was 76% (range 63-107%) predicted which improved to 88% (range 70-109%) predicted (p=0.03).

CONCLUSIONS: This small observational study indicates that bronchial thermoplasty can improve spirometric values in those patients who have moderate to severe obstruction.

CLINICAL IMPLICATIONS: Bronchial thermoplasty can improve spirometry as well as asthma control and asthma quality of life in patients with severe asthma and moderate to severe obstruction.

DISCLOSURE: The following authors have nothing to disclose: Andrew Porter, Brent Brown

No Product/Research Disclosure Information


Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543