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A 60-Year-Old Woman With PET Scan-Avid Lung Nodules and a History of a Ruptured Silicone Breast ImplantLung Nodules and Ruptured Breast Implant

Lioudmila V. Karnatovskaia, MD, FCCP; Andras Khoor, MD; Margaret M. Johnson, MD, FCCP; Joseph Kaplan, MD, FCCP
Author and Funding Information

From the Departments of Pulmonary and Critical Care Medicine (Drs Karnatovskaia, Johnson, and Kaplan) and the Department of Pathology (Dr Khoor), Mayo Clinic Florida, Jacksonville, FL.

CORRESPONDENCE TO: Lioudmila V. Karnatovskaia, MD, FCCP, Department of Pulmonary and Critical Care, Mayo Clinic, 200 First Rochester St NW, Gonda 18, Rochester, MN 55905; e-mail: karnatovskaia.lioudmila@mayo.edu


Dr Karnatovskaia is currently at the Department of Pulmonary and Critical Care Medicine, Mayo Clinic (Rochester, MN).

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2014;146(4):e138-e142. doi:10.1378/chest.14-0203
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A 60-year-old woman was referred to the pulmonary clinic for evaluation of lung nodules. Her medical history was notable for hypothyroidism, anxiety, and a ruptured breast implant for which incomplete surgical resection and evacuation had been performed 10 years previously. She was a lifelong nonsmoker and worked as a gym instructor. The patient denied occupational exposures and had not traveled recently. Medications included levothyroxine and alprazolam. Except for a 1-month history of occasional dry cough, the review of systems was negative. The patient’s physician queried whether the previously ruptured silicone breast implant may have played a role in the genesis of the nodules and referred the patient to our institution for further management. The lack of systemic symptoms relative to the degree of lung involvement provided an early diagnostic clue.

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