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Lung Protective Ventilation in DonorsLung Protective Ventilation in Donors: An Ounce of Prevention

Julia A. Klesney-Tait, MD, PhD; Michael Eberlein, MD, PhD
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From the Department of Internal Medicine, Division of Pulmonary and Critical Care, and Occupational Medicine, University of Iowa Carver College of Medicine.

CORRESPONDENCE TO: Julia Klesney-Tait, MD, PhD, Department of Internal Medicine, Division of Pulmonary and Critical Care, and Occupational Medicine, University of Iowa Carver College of Medicine, 200 Hawkins Dr, C34-12 GH, Iowa City, IA 52242; e-mail: julia-klesney-tait@uiowa.edu


FINANCIAL/NONFINANCIAL DISCLOSURES: The authors have reported to CHEST that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2014;146(1):4-6. doi:10.1378/chest.14-0163
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The evaluation, maintenance, and ultimate transplant of donor lungs remain one of the most challenging areas in transplantation. Donor lungs are often concomitantly injured at the time of donor death through infection, trauma, aspiration, and/or excessive smoking history. Although some progress has been made in terms of placing more organs over the past decade, lung use remains well below 50% of donors.1,2 There are a number of barriers to improving organ recovery in lung transplantation, including (1) the limited ability to accurately assess donor quality based on currently available preprocurement testing and (2) the limited evidence-based guidance regarding best practice in the ventilator management of potential donors.

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