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Contemporary Reviews in Critical Care Medicine |

Mechanical Ventilatory Support in Potential Lung Donor PatientsMechanical Ventilatory Support in Lung DonorsMechanical Ventilatory Support in Lung Donors

Ruchi Bansal, MD; Adebayo Esan, MD, FCCP; Dean Hess, PhD, RRT, FCCP; Luis F. Angel, MD; Stephanie M. Levine, MD, FCCP; Tony George, MD; Suhail Raoof, MD, FCCP
Author and Funding Information

From the Division of Pulmonary and Critical Care Medicine (Drs Bansal, Esan, George, and Raoof), New York Methodist Hospital, Brooklyn, NY; Respiratory Care Services (Dr Hess), Massachusetts General Hospital, Boston, MA; and the Division of Pulmonary and Critical Care Medicine (Drs Angel and Levine), University of Texas Health Science Center, San Antonio, TX.

CORRESPONDENCE TO: Suhail Raoof, MD, FCCP, New York Methodist Hospital, Pulmonary & Critical Care Medicine, 506 Sixth St, Brooklyn, NY 11215; e-mail: suhailraoof@gmail.com


FOR EDITORIAL COMMENT SEE PAGE 4

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2014;146(1):220-227. doi:10.1378/chest.12-2745
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Lung transplantation reduces mortality in patients with end-stage lung disease; however, only approximately 21% of lungs from potential donor patients undergo transplantation. A large number of donor lungs become categorized as unsuitable for lung transplantation as a result of lung injury around the time of brain death. Limiting this injury is key to increasing the number of successful lung procurements and subsequent transplants. This narrative review by a working group of pulmonologists, respiratory therapists, and lung transplant specialists elucidates principles of mechanical ventilatory support that can be used to limit lung injury in potential lung donor patients and examines the implementation of protocolized strategies in enhancing the procurement of donor lungs for transplantation.

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