0
Selected Reports |

Occupational Hypersensitivity Pneumonitis in a BakerHypersensitivity Pneumonitis in a Baker: A New Cause

Mathieu Gerfaud-Valentin, MD; Gabriel Reboux, PhD; Julie Traclet, MD; Françoise Thivolet-Béjui, MD; Jean-François Cordier, MD; Vincent Cottin, MD
Author and Funding Information

From the Hospices Civils de Lyon (Drs Gerfaud-Valentin, Traclet, Cordier, and Cottin), Hôpital Louis Pradel, Service de Pneumologie-Centre de référence national des maladies pulmonaires rares, Université Claude Bernard Lyon 1, Lyon; Laboratoire de parasitologie et mycologie (Dr Reboux), Centre hospitalier universitaire Jean Minjoz, Besançon; and Hospices Civils de Lyon (Dr Thivolet-Béjui), Groupe hospitalier est, Centre de biologie et pathologie est, Université Claude Bernard Lyon 1, Lyon, France.

Correspondence to: Vincent Cottin, MD, Hospices Civils de Lyon, Hôpital Louis Pradel, Service de Pneumologie-Centre de référence national des maladies pulmonaires rares, Université Claude Bernard Lyon 1, 28 avenue Doyen Lepine, f-69677 Lyon, France; e-mail: vincent.cottin@chu-lyon.fr


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2014;145(4):856-858. doi:10.1378/chest.13-1734
Text Size: A A A
Published online

Bakers are exposed daily to flour and may be susceptible to immunologic occupational diseases. A 30-year-old, nonsmoking, female baker was referred for progressive dyspnea on exertion, basal crackles on auscultation, restrictive lung function, decreased diffusing capacity of the lung for carbon monoxide, ground glass hyperdensities with a mosaic pattern on high-resolution CT scan, 25% lymphocytosis by BAL, and cellular chronic bronchiolitis with peribronchiolar interstitial inflammation by lung biopsy specimen. Cultures from flours isolated nine species, including Aspergillus fumigatus. Twenty-six antigens were tested. Serum-specific precipitins were found against A fumigatus, the flour mite Acarus siro, and total extracts from maize and oat. Outcome was favorable with cessation of occupational exposure to flours and transient therapy with prednisone and immunosuppressive agents. To our knowledge, this report is the first of a well-documented case of hypersensitivity pneumonitis due to sensitization to fungi- and mite-contaminated flours. Hypersensitivity pneumonitis—and not only asthma and allergic rhinitis—should be suspected in bakers with respiratory symptoms.

Figures in this Article

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543