Chest Infections |

The Risk of Tuberculosis in Contacts to Infectious TB Stratified by the Number of Cigarettes Smoked Per Day FREE TO VIEW

Kelsey Seal, MS; Vernon Hoeppner, MD; Assaad Al Azem, PhD; Nathan Osgood, PhD
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University of Saskatchewan, Saskatoon, SK, Canada

Chest. 2014;145(3_MeetingAbstracts):133A. doi:10.1378/chest.1836360
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SESSION TITLE: Tuberculosis Posters

SESSION TYPE: Poster Presentations

PRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PM

PURPOSE: This project investigated the relationship between smoking rates, ethnicity, and TB disease to determine whether there was a level of moking that increased the susceptibility to active tuberculosis amongst contacts to infectious TB.

METHODS: Subjects who were 18 years and older that had contact with infectious tuberculosis were enrolled. A questionnaire was completed via interview that included demographics, smokikng history, and whether they had TB. The presence of TB was confirmed by the TB Prevention and Control Program Saskatchewan. Smokers were categorized according to number of cigarettes smoked per day: ten or more (heavy), 5-9 (moderate), 1-4 (light), and non-smokers.

RESULTS: 103 contacts were interviewed. 47 were aboriginal, 36 were non-aboriginal, and 20 were foreign born. Amongst Aboriginal contacts 41 (87%) were smokers and 24 (51%) were heavy smokers, compared to 17 smokers (47%) with 12 (33%) heavy smokers amongst non-aboriginals and 4 smokers (20%) with 2 (10%) heavy smokers amongst foreign born contacts. Five cases of TB (5%) were found in the contacts, all amongst aboriginal heavy smokers or 21% of the heavy smoking aboriginal contacts.

CONCLUSIONS: Smoking was more prevalent amongst aboriginal contacts (87%) compared to non-aboriginals (47%) and foreign born contacts (20%), though amongst smokers the rates of heavy smoking were generally consistent across ethnic groups.All five cass of TB were found amongst aboriginal heavy smokers. Since the associateion between smoking and TB may be related to other life style factors, further exploration is needed.

CLINICAL IMPLICATIONS: Reducing amount smoked may help to decrease active TB in aboriginal contacts to infectious TB.

DISCLOSURE: The following authors have nothing to disclose: Kelsey Seal, Vernon Hoeppner, Assaad Al Azem, Nathan Osgood

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