Lung Cancer |

Angiosarcoma Presenting With Pulmonary Symptoms FREE TO VIEW

Esra Duman, MD; Hisam Alahdab, MD; Altan Kir, MD; Huseyin Baloglu, MD
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Anadolu Medical Center, Kocaeli, Turkey

Chest. 2014;145(3_MeetingAbstracts):314A. doi:10.1378/chest.1835944
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SESSION TITLE: Cancer Case Report Posters II

SESSION TYPE: Case Report Poster

PRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PM

INTRODUCTION: Angiosarcomas are rare neoplasms, accounting for approximately 1% of all soft tissue sarcomas.

CASE PRESENTATION: A 64 year old female patient presented with the complaints of dyspnea, cough, upper extremities and facial edema. Thorax CT showed a 9x8x6 cm mass located at anterior mediastinum, conglomerated bilateral lymphadenopathies and pericardial effusion. Bronchoscopic examination revealed tumoral invasion at right 1/3 lower tracheal wall but biopsies were nondiagnostic. Based on clinical and imaging findings the patient was accepted as an advanced stage lung cancer and treated with chemotherapy containing cisplatin, etoposide and steroid . The facial edema had partially regressed but dyspnea had increased. At this stage the patient was referred to our clinic. Upon physical examination vital signs were normal; except for thoracic collateral venous dilatation, facial edema and diffuse inspiratory wheezing. Mediastinoscopy was performed, biopsies revealed a tumour with CD 31 reactive neoplastic cell proliferation with vascular formation. Angiosarcoma was diagnosed with histomorphologic and immunophenotypic properties.

DISCUSSION: Clinical decision supported only by imaging techniques can mislead physicians, all appropriate diagnostic methods needed to get the tissue diagnosis should be used in malignancy patients.

CONCLUSIONS: Histopathologic tissue diagnosis is essential and inevitable in malignancy patients and should be the main tool to guide the treatment.

Reference #1: Primary pulmonary angiosarcoma, an exceptional neoplasm with a poor prognosis: reports of two cases and review of the literature. Obeso Carillo GA, García Fontán EM, Cañizares Carretero MA, Pérez Pedrosa A. Gen Thorac Cardiovasc Surg. 2013 Jan 11

DISCLOSURE: The following authors have nothing to disclose: Esra Duman, Hisam Alahdab, Altan Kir, Huseyin Baloglu

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