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Obstructive Lung Diseases |

Cardiovascular Alterations in COPD-What Hurts the Patient Most?

Deepak Singh, MD
Author and Funding Information

Govt. of Rajasthan, INDIA, Bharatpur, India


Chest. 2014;145(3_MeetingAbstracts):396A. doi:10.1378/chest.1832675
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Abstract

SESSION TITLE: COPD Comorbidity Posters

SESSION TYPE: Poster Presentations

PRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PM

PURPOSE: 1.To observe cardiovascular (both left as well as right heart function) effects in COPD patients. 2.To evaluate role of thorough cardiovascular check up as a routine in COPD patient including ECG and ECHO study to manage the COP syndrome.

METHODS: This study had 50 patients of COPD from the OPD and IPD patients in KN chest Hospital, Jodhpur. These patients belonging in majority to moderate (II) and severe (III) GOLD(Global Initiative on obstructive Lung Disease) stages were analyzed by Blood profile, BMI, Resting oxygen saturation, CX Ray, Spirometry, ECG and Echocardiography. Main objective was to observe cardiovascular effects in these COPD patients. The statistical analysis was done using Chi Square and Student ‘t’ test.

RESULTS: Maximum patients had Emphysema predominant on CX ray, BMI was low, CRP was raised and were hypoxic, belonged to MMRC grade II and III with low Hemoglobin and Hematocrit. The chief cardiovascular alterations were LVDD (56%), Pulmonary hypertension (48%), Right Ventricular enlargement (46%) and Right atrial enlargement (32%) while LVSD (18%), LA enlargement (10%), LVH (10%) and Cor Pulmonale (18%) besides left venricular mass increases with disease advancement .These changes were significantly associated with the stage of COPD and increasing MMRC grades of dyspnea.

CONCLUSIONS: The cardiovascular alterations in COPD are far too common especially LVDD, which remains grossly unmanaged and can occur in COPD independently and before Rt. sided effects and PAH occur. So diastolic dysfunction should be sought actively in COPD besides the right sided changes and pulmonary hypertension.

CLINICAL IMPLICATIONS: Rt. and Lt. both sided cardiovascular alterations can give rise to clinical worsening and exacerbation in COPD. Most correctable factor is Hypoxia. Treatment of condition is rewarding. So all patients of COPD especially of Moderate and Severe stages should have thorough Cardiovascular check up and Holistic management.

DISCLOSURE: The following authors have nothing to disclose: Deepak Singh

No Product/Research Disclosure Information


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