Chest Infections |

Pulmonary Hamartoma Mimicking Pulmonary Tuberculoma: An Unusual Presentation in a Patient With Positive IGRA Test FREE TO VIEW

Georgios Athanasiou, MS; Ioan Arghir, MS; Valerios Kortzis, MS; Paraschiva Postolache, PhD; Oana Arghir, PhD
Author and Funding Information

Faculty of Medicine Ovidius University, Constanta, Romania

Chest. 2014;145(3_MeetingAbstracts):88A. doi:10.1378/chest.1825039
Text Size: A A A
Published online


SESSION TITLE: Tuberculosis Case Report Posters

SESSION TYPE: Case Report Poster

PRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PM

INTRODUCTION: To reveal the risk of pulmonary hamartoma mimicking pulmonary tuberculoma. To explore the varied and unusual, clinical and radiological pattern of pulmonary hamartoma.

CASE PRESENTATION: We report an unusual presentation of a stable solitary pulmonary nodule (SPN) in the lingula of a 63 yr-old white female patient, for 13 years. Suddenly, in the 14th year of evolution, she was admitted in our hospital for recurent hemoptysis and positive result of QuantiFERON TB Gold testing. CT scan reveals SPN with central lose substance and eccentric calcification area, mimicking pulmonary tuberculoma. She was subsequently treated for pulmonary tuberculosis. After 2 months of therapy, the nodule doubled initial volume and surgical intervention was recommended. Histopathologic exam confirmed lung hamartoma.The case survived.

DISCUSSION: Lung hamartomas are more common in men than in women, and grow slowly over time, doubling in size about ever 4.2 years, according to the National Institute of Health.(1) Hamartoma, as benign tumors of the lung, may present additional diagnostic difficulties in endemic area of tuberculosis.Tuberculoma, if not diagnosed and treated early, could cause significant extensive tuberculosis lung disease, while hamartoma could cause lung cancer.(2) The histology of the parenchymal mass 45 mm in size reveals the predominance of adipose and leiomyomatous differentiation and only one eccentric calcification caused by chondroid differentiation.

CONCLUSIONS: The rapidly growing in size of the tumour, positive IGRA and the fatty histologic pattern make it an unusual presentation.

Reference #1: http://www.ehow.com/about_5548404_symptoms-hamartoma.html

Reference #2: Ribet CM, Jaillard-Thery S, Nuttens MC: Pulmonary hamartoma and malignancy. J Thorac Cardiovasc Surg 1994, 107(2):611-4.

DISCLOSURE: The following authors have nothing to disclose: Georgios Athanasiou, Ioan Arghir, Valerios Kortzis, Paraschiva Postolache, Oana Arghir

No Product/Research Disclosure Information




Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543