Sleep Disorders |

Roles of Gender in Obstructive Sleep Apnea Syndrome: Exploring Differences FREE TO VIEW

Rosa Mirambeaux Villalona, MD; Eva Mañas Baena, PhD; Paola Arrieta Narvaez, MD; Maria Salazar, NP; Jonathan Cámara Fernández, MD; Carolina Gotera, MD; Carolina Jurkojc Mohremberger, MD; Deisy Barrios Barreto, MD; Patricia Lazo Meneses, MD; Patricia Castro Acosta, MD; Maria Galarza Jimenez, MD; Salvador Diaz Lobato, PhD; Sagrario Mayoralas Alises, PhD; Esteban Perez Rodriguez, PhD; Javier Garcia Leaniz, PhD
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Ramon y Cajal Hospital, Madrid, Spain

Chest. 2014;145(3_MeetingAbstracts):574A. doi:10.1378/chest.1823576
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SESSION TITLE: Sleep Posters

SESSION TYPE: Poster Presentations

PRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PM

PURPOSE: This study investigated gender differences in a patients cohort with sleep apnea.

METHODS: A retrospective review of patients referred to our sleep laboratory during 2006-2011 was completed.

RESULTS: We studied 146 patients, 98 males (67 %) and 48 women (33 %). Women were slightly older (58 years+/-12.3 vs 56 years+/-13.1, p 0.2), had higher body mass index (36.6, SD 8.6 vs 30.7, SD 4.7; p 0.01), and lower apnea/hypopnea index (AHI) at the time of diagnosis (20.2, SD 18 vs 29, SD 21, p 0.042). Insomnia was more prevalent in the women (31 % vs 16 %, p 0.01). Daytime sleepiness (Epworth sleepiness scale) appeared more raised in the men (15.09+/- 4.2 vs 10.53 +/-5.5; p 0.02). The proportion of positive diagnoses was similar (60.4% in women and 63.3% in men). There was similar prevalence of HTA, DM, ischemic heart disease and depression in the men and the women.

CONCLUSIONS: Women reported significantly less subjective daytime sleepiness, more insomnia, a higher body mass index, as well as a minor AHI. Some of these findings have been described before. Further larger studies may help confirm, as well as clarify, mechanisms that underlie the gender differences that we have noted. Clinicians need to be aware of these differences when assessing women for the possibility of sleep apnea in order to allow a correct management of the disease.

CLINICAL IMPLICATIONS: Knowledge about these gender-related differences in clinical features of sleep apnea may contribute to an increased awareness and improved diagnosis.

DISCLOSURE: The following authors have nothing to disclose: Rosa Mirambeaux Villalona, Eva Mañas Baena, Paola Arrieta Narvaez, Maria Salazar, Jonathan Cámara Fernández, Carolina Gotera, Carolina Jurkojc Mohremberger, Deisy Barrios Barreto, Patricia Lazo Meneses, Patricia Castro Acosta, Maria Galarza Jimenez, Salvador Diaz Lobato, Sagrario Mayoralas Alises, Esteban Perez Rodriguez, Javier Garcia Leaniz

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