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Lung Cancer |

Primary Paraganglioma of the Lung

Giuseppe Fiorentino, MD; Anna Annunziata, MD; Rosa Cauteruccio, MD; Raffaele Cobuccio, MD; Mario Caputi, MD
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Monaldi Hospital, Naples, Italy


Chest. 2014;145(3_MeetingAbstracts):305A. doi:10.1378/chest.1815156
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Abstract

SESSION TITLE: Cancer Case Report Posters II

SESSION TYPE: Case Report Poster

PRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PM

INTRODUCTION: Primary paraganglioma of the lung is a rare tumor of which few cases are reported in literature.

CASE PRESENTATION: We report the case of an 63-year man who presented with cough, intermittent palpitations and dyspnea. Contrast-enhanced computed tomography of the chest revealed in the middle lobe, a rounded, high-density lesion in presence of irregular profiles with a diameter of 24 mm. The lesion was suspicious for malignancy. Fine needle aspiration cells was performed. The cytological report was positive for malignant cells. Surgical resection was the treatment of choice. The results of the biochemical tests and post-operative histological examination allow definitive diagnosis: primary pulmonary paraganglioma.

DISCUSSION: Primitive lung paragangliomas are often discovered incidentally upon examination of routine chest radiographs, and patients are free of symptoms and hypertension. From the literature about 10% of paragangliomas are malignant and all patients have been treated surgically with either local excision or lobectomy.

CONCLUSIONS: Paragangliomas are identified and characterized with the use of computed tomography and other imaging methods, but for definitive diagnosis, histopathologic evaluation is necessary. There are, however, no histological or biochemical markers that can predict reliably the malignant tendency of these tumours.

Reference #1: Dana Erickson et al. Benign Paragangliomas: Clinical Presentation and Treatment Outcomes in 236 Patients , J Clin Endocrinol Metab, November 2001, 86(11):5210-5216);

DISCLOSURE: The following authors have nothing to disclose: Giuseppe Fiorentino, Anna Annunziata, Rosa Cauteruccio, Raffaele Cobuccio, Mario Caputi

No Product/Research Disclosure Information


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