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Usefulness of FeNO in the Diagnosis of Chronic Cough FREE TO VIEW

Vijo Poulose, MD
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CGH, Singapore, Singapore

Chest. 2014;145(3_MeetingAbstracts):567A. doi:10.1378/chest.1791428
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SESSION TITLE: Symptoms of Respiratory Disease Posters

SESSION TYPE: Poster Presentations

PRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PM

PURPOSE: FeNO (fractional exhaled nitric oxide) may help identify cases of NAEB (nonasthmatic eosinophilic bronchitis) or asthma. The aim of this study is to evaluate the utility of FeNO in the evaluation of chronic cough

METHODS: Chart review of patients referred to the respiratory clinic for evaluation of chronic cough over a 3 year period (January 2010 to December 2012) was performed. FeNO testing was only done when the diagnosis was not clear from the initial history, physical exam or radiography. A FeNO level > 25 ppb was considered high. A diagnosis of NAEB was made only in patients with a high FeNO, negative methacholine test and responded to inhaled/oral steroids

RESULTS: Of the 200 patients seen, FeNO testing was done in 24 patients, of which 3 patients defaulted follow-up. In the remaining 21 cases, FeNO helped provide a diagnosis in 6 (NAEB - 4, asthma -2)

CONCLUSIONS: FeNO testing is a useful, non-invasive tool that can aid in the evaluation of chronic cough, especially considering the practical difficulty in sending sputum for eosinophilia testing

CLINICAL IMPLICATIONS: In patients where the etiology of cough is not readily apparent from the history, physical exam or radiography, FeNO testing can be considered

DISCLOSURE: The following authors have nothing to disclose: Vijo Poulose

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