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Postgraduate Education Corner: Pulmonary, Critical Care, and Sleep Pearls |

A 25-Year-Old Man With Fulminant Hepatic Failure After Treatment With CorticosteroidsA 25-Year-Old Man With Fulminant Hepatic Failure

Joshua L. Denson, MD; Abigail Maller, MD; Christine A. Beckwith, MD; David R. Schwartz, MD
Author and Funding Information

From the Internal Medicine Residency Program (Drs Denson, Maller, and Beckwith) and Division of Pulmonary, Critical Care, and Sleep Medicine (Dr Schwartz), Department of Medicine, NYU Langone Medical Center, New York, NY.

Correspondence to: David Schwartz, MD, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, NYU Langone Medical Center, 530 First Ave, New York, NY 10016; e-mail: David.Schwartz@nyumc.org


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2013;144(5):1717-1719. doi:10.1378/chest.13-1056
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FlewettTHParkerRGFPhilipWM. Acute hepatitis due to herpes simplex virus in an adult. J Clin Pathol. 1969;22(1):60-66.WhitleyRLakemanADNahmiasARoizmanB. DNA restriction-enzyme analysis of herpes simplex virus isolates obtained from patients with encephalitis. N Engl J Med. 1982;307(17):1060-1062.MiyazakiYAkizukiSSakaokaHYamamotoSTeraoH. Disseminated infection of herpes simplex virus with fulminant hepatitis in a healthy adult. A case report. APMIS. 1991;99(11):1001-1007.KaufmanBGandhiSALouieERizziRIlleiP. Herpes simplex virus hepatitis: case report and review. Clin Infect Dis. 1997;24(3):334-338.ChungABFasN. Successful acyclovir treatment of herpes simplex type 2 hepatitis in a patient with systemic lupus erythematosus: a case report and meta analysis. Am J Med Sci. 1998;316(6):404-407.IrieHKoyamaHKuboH. Herpes simplex virus hepatitis in macrophage-depleted mice: the role of massive, apoptotic cell death in pathogenesis. J Gen Virol. 1998;79(pt 5):1225-1231.IchaiPRoque AfonsoAMSebaghM. Herpes simplex virus-associated acute liver failure: a difficult diagnosis with a poor prognosis. Liver Transpl. 2005;11(12):1550-1555.MontalbanoMSlapak-GreenGINeffGW. Fulminant hepatic failure from herpes simplex virus: post liver transplantation acyclovir therapy and literature review. Transplant Proc. 2005;37(10):4393-4396.NorvellJPBleiATJovanovicBDLevitskyJ. Herpes simplex virus hepatitis: an analysis of the published literature and institutional cases. Liver Transpl. 2007;13(10):1428-1434.RiedigerCSauerPMatevossianEMüllerMWBüchlerPFriessH. Herpes simplex virus sepsis and acute liver failure. Clin Transplant. 2009;23(suppl 21):37-41.

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