0
Point/Counterpoint Editorials |

Rebuttal From Dr HallRebuttal

Jesse B. Hall, MD, FCCP
Author and Funding Information

From the Department of Anesthesia & Critical Care and Section of Pulmonary and Critical Care Medicine, Pritzker School of Medicine, The University of Chicago.

Correspondence to: Jesse B. Hall, MD, FCCP, Section of Pulmonary and Critical Care Medicine, Pritzker School of Medicine, The University of Chicago, 924 E 57th St, Ste 104, Chicago, IL 60637-5415; e-mail: jhall@medicine.bsd.uchicago.edu


Financial/nonfinancial disclosures: The author has reported to CHEST that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2013;144(5):1445-1446. doi:10.1378/chest.13-1461
Text Size: A A A
Published online

Extract

Dr Sessler has provided a number of arguments in an attempt to counter or at least soften a positive interpretation of the study supporting a role for neuromuscular blockade (NMB) as a therapeutic adjunct during mechanical ventilation of patients with severe ARDS.1,2 Although these arguments are thoughtful and well presented, even in aggregate they do not dissuade me from my initial position.

He points out that there may be a disconnect between the patients reported in the trial and those whom practicing physicians actually care for, as suggested by the fact that only 25% of eligible patients were enrolled. For better or for worse, this is the reality of clinical trials and is not different from the usual circumstances of trying to apply evidence from trials to practice. I believe that we are better off with the results of trials conducted under a careful protocol than being limited to observational data from real-world circumstances.

First Page Preview

View Large
First page PDF preview

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543