0
Cardiovascular Disease |

Pulmonary Vein Thrombosis: A Rare Entity

Sandeep Sahay, MD; Robert Lodato, MD
Author and Funding Information

University of Texas, Health Science Center at Houston, Houston, TX


Chest. 2013;144(4_MeetingAbstracts):129A. doi:10.1378/chest.1705212
Text Size: A A A
Published online

Abstract

SESSION TITLE: Cardiovascular Case Report Posters II

SESSION TYPE: Affiliate Case Report Poster

PRESENTED ON: Tuesday, October 29, 2013 at 01:30 PM - 02:30 PM

INTRODUCTION: Idiopathic pulmonary vein thrombosis (PVT) is rare. Although it is a potentially life threatening condition, it is easy to misdiagnose because of the non-specific symptoms.

CASE PRESENTATION: A 48-year-old man with diabetes mellitus, hypertension, and pancreatic arteriovenous malformations presented after an episode of syncope. Patient denied any symptoms of cough, dyspnea, hemoptysis and pleuritic chest pain. Initial evaluation revealed tachycardia and orthostatic hypotension. He was given intravenous fluid resuscitation. On the second day, his orthostatic hypotension resolved, but the tachycardia persisted. His heart rhythm remained sinus with rate between 120-140/minute. A week later, for the persistence of tachycardia, a computed tomographic angiogram (CTA) of the chest was performed for the suspected pulmonary embolism. It revealed thrombosis of the left inferior pulmonary vein with associated lung parenchymal changes suggesting venous infarct (Figure 1). Anticoagulation with intravenous unfractionated heparin was begun. One week later, a second CTA, showed complete resolution of the pulmonary vein thrombus and resolution of the associated parenchymal changes (Figure 2). The tachycardia resolved, and he was discharged home on anticoagulation therapy with oral warfarin. Evaluation for hypercoagulable state was negative.

DISCUSSION: Idiopathic pulmonary vein thrombosis is difficult to diagnose clinically, but it can lead to potentially life threatening complications. Secondary causes of PVT include lung cancer, lung transplantation, left atrial thrombus, and pulmonary lobectomy. PVT can present as pulmonary infarction with cough, dyspnea, pleuritic chest pain and hemoptysis or, in a more insidious manner, as progressive or recurrent pulmonary edema. PVT occurs in approximately 15% of the post lung transplant patients, most frequently at the anastomotic site, and can lead to early postoperative allograft failure. Complications of PVT include systemic embolization.

CONCLUSIONS: Idiopathic pulmonary vein thrombosis has been only rarely reported. This case adds to current information by showing its potentially rapid resolution (within a week) with anticoagulation.

Reference #1: Schulman LL et al. Four-Year Prospective Study of Pulmonary Venous Thrombosis After Lung Transplantation. J Am Soc Echocardiogr 2001;14:806-12

Reference #2: Jun-ping WU et al. Idiopathic pulmonary vein thrombosis extending to left atrium: a case report with a literature review. Chinese Medical Journal 2012;125(6):1197-1200

Reference #3: Cavaco RA, Kaul S, Chapman T, et al. Idiopathic pulmonary fibrosis associated with pulmonary vein thrombosis: a case report. Cases J. 2009 Dec 7;2:9156.

DISCLOSURE: The following authors have nothing to disclose: Sandeep Sahay, Robert Lodato

No Product/Research Disclosure Information


Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
Thrombolysis for acute deep vein thrombosis. Cochrane Database Syst Rev Published online Nov 10, 2016;
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543