Diffuse Lung Disease |

Occupational SHS Exposure Within Semi-Open Air Venues and Tobacco Specific Carcinogen Uptake FREE TO VIEW

Constantine Vardavas, PhD; Maria Karampela, MD; Israel Agaku, MPH; Antonis Myridakis, MS; Antonis Kouvarakis, PhD; Euripides Stephanou, PhD; Gregory Connolly, MPH; Panagiotis Behrakis, PhD
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Harvard School of Public Health, Boston, MA

Chest. 2013;144(4_MeetingAbstracts):481A. doi:10.1378/chest.1704791
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SESSION TITLE: Occupational/ Environmental Lung Disease Posters

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 30, 2013 at 01:30 PM - 02:30 PM

PURPOSE: Secondhand smoke is a well regulated and defined occupational hazard. The association though between occupational SHS exposure in semi-open air venues and tobacco specific carcinogen uptake has not yet been assessed.

METHODS: A cross sectional survey of 49 semi-open air venues in Athens, Greece was performed during the summer of 2009, prior to the adoption of the national smoke free legislation. All venues had at least one entire wall open to allow for free air exchange between the outside and the inside. Indoor concentrations of PM2.5 attributable to SHS were assessed with a TSI Sidepack. One non-smoking employee responsible for indoor and outdoor table service from each venue was requested to provide a post shift urine sample, for analysis of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).

RESULTS: Post work shift NNAL concentrations were correlated with work shift PM2.5 concentrations attributable to SHS (r=0.376, p=0.0076). Post work shift NNAL concentrations were found to be higher among employees exposed to work shift SHS at concentrations >150μg/m3 -with mean NNAL concentrations of 161pg/ml- than those relatively not exposed to SHS (concentrations <50μg/m3) -with mean NNAL concentrations of 33pg/ml. Moreover, NNAL concentrations were found to be higher among employees sampled during the weekend (91pg/ml vs. 76pg/ml) and after 8pm (95pg/ml vs. 82pg/ml), in comparison to those sampled during the week or before 8pm. Controlling for the above two factors within a linear regression analysis, NNAL concentrations increased by 9.5%, per 10μg/m3 of PM2.5 concentrations attributable to SHS.

CONCLUSIONS: Our results indicate that maintaining open/sliding walls as a means of reducing patron and employee SHS exposure is not effective in eliminating exposure to SHS and tobacco specific carcinogen uptake.

CLINICAL IMPLICATIONS: Clinicans should advise their patients that SHS exposure can lead to carcinogen uptake even in semi-open areas

DISCLOSURE: The following authors have nothing to disclose: Constantine Vardavas, Maria Karampela, Israel Agaku, Antonis Myridakis, Antonis Kouvarakis, Euripides Stephanou, Gregory Connolly, Panagiotis Behrakis

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