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Obstructive Lung Diseases |

Pulmonary Embolism as a Cause of Acute Exacerbation of COPD in Patients With Exacerbation of Unknown Etiology

Rafi Jan, MD
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SKIMS, Srinagar, India


Chest. 2013;144(4_MeetingAbstracts):680A. doi:10.1378/chest.1704030
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Abstract

SESSION TITLE: Acute exacerbations of COPD

SESSION TYPE: Original Investigation Slide

PRESENTED ON: Wednesday, October 30, 2013 at 02:45 PM - 04:15 PM

PURPOSE: To find the incidence of pulmonary embolism in patients with acute exacerbation of COPD of unknown etiology

METHODS: : 100 diagnosed cases of COPD patients with acute exacerbation of unknown etiology were taken for study simplified Geneva sores applied and subjected to investigations(baseline and advanced) important one being ; D-dimer,leg ultrasound and finally diagnosed by intervention CT Pulmonary angiography

RESULTS: out of total 100 patients57% were males and 43% were females mean age was 66.3 years.D-dimer was done in all patients DVT was seen in 9 patients, 14% had pulmonary embolism confirmed by CT angiography ( 50% were males,and50 %were females).Out of 14 patients with pulmonary embolism 6 patients had central, 5 patients segmental, and 2l patients had sub segmental pulmonary embolism. History of Venous thromboembolisim, Pleuritic chest pain ,Hemoptysis(p_value <0.001 ,risk ratio of0.135) Low BP and increased heart rate(p-value0.001), Decreased platelet count, Increased PH ,Decreased PCO2, Increased serum Sodium levels and Urea levels . Simplified Geneva scores showed high scores in pulmonary embolism patients (p-value<0.0001) are predictors of pulmonary embolism in patients with acute exacerbation of COPD

CONCLUSIONS: Pulmonary embolism should be considered while evaluating patients of acute excacerebration of a COPD of unknown etiology and proper work up on the lines of pulmonary embolism should be started. in diagnosing. Multi slice CT pulmonary angiography effective in diagnosing pulmonary embolism even up to sbsegemental level

CLINICAL IMPLICATIONS: Pulmonary embolism is one of the important causes of acute exacerbation of COPD

DISCLOSURE: The following authors have nothing to disclose: Rafi Jan

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