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Transplantation |

Geriatric Lung Transplantation

Shrestha Patel, DO; Jordan Terasaki, MD; Shiwan Shah, DO; Gisele Lombard, RN; Margaret James, RN; Daniel Beckles, MD; Scott Lick, MD; Vincent Valentine, MD
Author and Funding Information

University of Texas Medical Branch, Galveston, TX


Chest. 2013;144(4_MeetingAbstracts):1016A. doi:10.1378/chest.1704019
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Abstract

SESSION TITLE: Lung Transplantation Posters

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 30, 2013 at 01:30 PM - 02:30 PM

PURPOSE: Advanced age is a relative contraindication for lung transplantation (LT). Despite this, there has been an 11-fold increase over the last quarter century in the number of LT procedures in patients ≥ 65-years-old. Nevertheless, outcomes are inferior to younger patients with a half-life of 3.6 years. We compare the outcomes of single lung transplant recipients ≥ 65 to those < 65 years.

METHODS: We reviewed the charts of all single LT recipients at our institution from 2008 to 2012 for demographic, preoperative, postoperative, and survival data.

RESULTS: Thirteen patients were included, seven ≥65 and six < 65 years. The median ages in the two groups were 73.2 and 59.6 years, respectively (p=0.003). No other differences in baseline characteristics, including body mass index, indications for transplant, pre-transplant albumin, or lung allocation scores were noted. The initial ventilator time was higher in the older group (17 vs 6.1 hours, p=0.05). Nevertheless, ICU (3 vs 2 days, p=0.11) and hospital length of stay (12 vs 9.5, p=0.35) were similar. Long term improvements in pulmonary function and change in kidney function were not different. One year survival was 100% in the ≥65 year group versus 83% in the <65 year group with a median follow up of 367 and 476 days, respectively.

CONCLUSIONS: Transplantation of selected geriatric patients can be performed with acceptable short and long term outcomes.

CLINICAL IMPLICATIONS: This study provides further support for offering lung transplantation to carefully selected patients ≥ 65 years of age.

DISCLOSURE: The following authors have nothing to disclose: Shrestha Patel, Jordan Terasaki, Shiwan Shah, Gisele Lombard, Margaret James, Daniel Beckles, Scott Lick, Vincent Valentine

No Product/Research Disclosure Information


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