Obstructive Lung Diseases |

The Role of Female Gender in COPD Exacerbation FREE TO VIEW

Hatice Kilic, MD; Nurdan Kokturk, MD; Gülcin Sari, MD; Mustafa Cakir, MD
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Ankara Ataturk Education and Research Hospital, Ankara, Turkey

Chest. 2013;144(4_MeetingAbstracts):699A. doi:10.1378/chest.1703887
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SESSION TITLE: COPD Diagnosis & Evaluation Posters

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 30, 2013 at 01:30 PM - 02:30 PM

PURPOSE: To evaluate gender differences in the clinical characteristics of COPD exacerbations admitted to the pulmonary clinic.

METHODS: A total of 384 COPD patients were evaluated retrospectively for their exacerbation characteristics.

RESULTS: One hundred nine (28%) female and 275 (72%) male patients with COPD were included in the study. FEV1% was higher in females than males (42.6 % vs 35 %; p=0.00, respectively). No significant difference was identified according to gender in number of exacerbations, ICU admission for the last year and number of entubation (p>0.05). However, compared with men; women had higher values in exacerbation rates, disease severity, number and length of hospitalization for the last year. Tracheobronchial infections were in similar rate in exacerbations both in women (%41.6) and in men (%36,3). Among other etiologies of exacerbation pneumonia was more frequent in men [(35%) vs (11%)] while pulmonary embolism and non-adherence to treatment was more frequent in women [(4,6%) vs (2.2%) and (17,4%) vs (7,1%), respectively] (p=0,001 for all comparisons)] .

CONCLUSIONS: This study highlighted that there is significant difference in terms of hospitalization and disease severity in exacerbation pattern according to the gender.

CLINICAL IMPLICATIONS: It is epidemiologically important to determine whether the results of exacerbation of COPD are different in females. This datas might be effect to the therapeutic and clinic implications in the future. The results of our study need to be confirmed with further expanded women population.

DISCLOSURE: The following authors have nothing to disclose: Hatice Kilic, Nurdan Kokturk, Gülcin Sari, Mustafa Cakir

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