SESSION TITLE: Respiratory Infections Posters
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Wednesday, October 30, 2013 at 01:30 PM - 02:30 PM
PURPOSE: This study aimed to determine the factors associated with culture results and to evaluate the effect of culture results on treatment outcomes in patients with community-acquired pneumonia (CAP) and healthcare-associated pneumonia (HCAP).
METHODS: Turkish Thoracic Society Respiratory System Infections Study Group database (TURCAP) includes all patients admitted to the hospital for CAP and HCAP. The data from five tertiary care centers retrieved from the database were evaluated according to the results of sputum and blood cultures.
RESULTS: Sputum cultures were performed in 297 of 537 (mean age 66.1 ± 15.8 years, 365 males) patients who were registered to the database and causative agents were isolated in 67 (22.6%). The most common pathogens were P. aeruginosa (n=15) and S. pneumoniae (n=10). Blood cultures were performed in 220 patients and causative agents were isolated in 15 (6.8%). The most common pathogen was S. pneumoniae (n=7). The patients in whom a pathogen was isolated from sputum were older (67.9±14.2 vs. 62.5±17.1 years) and had lower leukocyte count (8404.4±11942.7 vs. 13163.5±7327.3/mm3), higher PSI score (109.3±35.7 vs. 96.7±36.6), more comorbidities (100% vs. 80.9%) had a more frequent history of hospitalization two or more times (31.3% vs. 17.8%), more frequent use of inhaler and oral steroids (35.8% vs.% 23.0 and 10.4% vs. 7.8%, respectively) and less use of antibiotic in the past 3 months (17.9% vs 27.8%). The patients in whom the blood culture was positive had higher leukocyte count (19522.7±19164.0 vs. 13524.9±7036.7/mm3) and PSI scores (118.5±39.9 vs. 95.9±37.1). Treatment responses were similar in patients with positive and negative cultures.
CONCLUSIONS: No bacteriologic analysis was performed in a significant proportion of patients admitted to the hospital for pneumonia and causative agents were identified in a minority of the patients. Identification of a causative agent did not affect the treatment results.
CLINICAL IMPLICATIONS: The participating centers need to put more efforts to comply with national guidelines and perform bacteriologic analyses in admitted patients, after which the treatment outcomes must be reevaluated.
DISCLOSURE: The following authors have nothing to disclose: Sezai Tasbakan, Canan Gunduz, Abdullah Sayiner, Aykut Cilli, Burcu Karaboga, Oguz Kilinc, Oznur Kilic, Aysin Sakar Coskun, Cemile Cetinkaya, Armagan Hazar, Fatma Tokgoz
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