SESSION TITLE: DVT/PE/Pulmonary Hypertension Posters
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Wednesday, October 30, 2013 at 01:30 PM - 02:30 PM
PURPOSE: Obesity defined as body mass index(BMI) ≥30kg/m2 has been shown to be a risk factor and a prognosticator in many populations. However, whether obesity is specifically a prognosticator for PE is not well known. This study examined whether any BMI values are associated with severity of PE using simplified pulmonary embolism severity index (sPESI) as an outcome.
METHODS: 194 patients with BMI between 14 and 88 kg/m2 (44.3‰ males, mean age 59±18 years, median BMI 30.3 kg/m2) who was diagnosed with PE were included in this cross-sectional study. Relevant clinical data was collected. High-risk group was defined as sPESI more than zero. Appropriate descriptive statistics and statistical tests were performed. Statistical significance was defined as p value less than 0.05.
RESULTS: BMI, percentage of patients being overweight or obese, percentage of patients using oral hormonal contraceptives and hemoglobin level were statistically significantly higher in a low-risk group. Univariate binomial logistic regression analysis showed that overweight or obesity (defined as BMI>25kg/m2) was an independent variable predicting being in a low-risk group with OR of 2.39(95%confidence interval 1.10, 5.21) and p value of 0.028
CONCLUSIONS: Paradoxically, overweight or obese patients with PE have better prognostic outcomes compared to underweight or normal weight patients defined by sPESI in our study.
CLINICAL IMPLICATIONS: BMI might be a prognosticator in patients with PE. Being overweight or obese is associated with less severity in PE.
DISCLOSURE: The following authors have nothing to disclose: Nongnooch Poowanawittayakom, Kongkiat Chaikriangkrai, Prangthip Charoenpong, Clifton Clarke
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