Sleep Disorders |

Obesity and Obstructive Sleep Apnea in Acromegalic Patients FREE TO VIEW

Doina-Adina Todea, PhD; Paraschiva Postolache, PhD; Andreea-Cristina Herescu, PhD; Andreea-Codruta Coman, PhD; Loredana-Elena Rosca, PhD
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"Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania

Chest. 2013;144(4_MeetingAbstracts):1000A. doi:10.1378/chest.1702602
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SESSION TITLE: Sleep Posters

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 30, 2013 at 01:30 PM - 02:30 PM

PURPOSE: Daytime sleepiness, snoring and sleep disordered breathing (including obstructive sleep apnea syndrome - OSAS) are commonly encountered in patients with acromegaly. The prevalence OSAS is increasing worldwide, in part linked to epidemic of obesity. The aim of the study was to estimate the presence of obesity and the severity of OSAS in patients with acromegaly.

METHODS: Material and methods: between Jan 2009 and Jan 2013 - 35 patients with acromegaly were evaluated for OSAS. Age, gender, symptoms, neck and abdominal circumference, body-mass index (BMI), smoking and alcohol drinking history, cardiovascular findings, Epworth sleepiness scale - ESS, and sleep apnea polygraphy (apnea hypopnea index - AHI, oxygen saturation - SpO2, oxygen desaturation index - ODI) were collected to all patients.

RESULTS: Results: 34 patients were with OSAS, 4 patients were with normal weight (mean AHI= 20.32; SpO2 average =95.75; ODI =5.7; ESS=8.25), 15 were overweight (mean AHI =30.89; SpO2 average =93.80; ODI =22.56; ESS=7.86), 11 with class I obesity (mean AHI=23.53; SpO2 average =94.10; ODI =18.51; ESS=8.36), 3 with class II obesity (mean AHI= 42.7; SpO2 average =92.67; ODI =27.00; ESS=11.67), 1 with class III obesity (mean AHI=63.00; SpO2 average =91.00; ODI =57; ESS=19). 10 cases (28.6) had mild OSAS, 12 cases (34.3%) moderate OSAS and 12 (34.3%) severe OSAS.

CONCLUSIONS: Conclusions: The majority of acromegalic patients are overweight and obese with moderate and severe forms of OSAS.

CLINICAL IMPLICATIONS: Knowledge of the clinical and functional aspects of the sleep apnea in patients with acromegaly.

DISCLOSURE: The following authors have nothing to disclose: Doina-Adina Todea, Paraschiva Postolache, Andreea-Cristina Herescu, Andreea-Codruta Coman, Loredana-Elena Rosca

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