SESSION TITLE: Lung, Exercise and Aging
SESSION TYPE: Original Investigation Slide
PRESENTED ON: Sunday, October 27, 2013 at 10:45 AM - 11:45 AM
PURPOSE: Cognitive decline is common in older people. It is a risk factor to develop cognitive impairment and dementia. However, very little data is available that examine the relationship between cognitive decline and lung function in older-people with longer-term follow-up. Aims: We examined the association between cognitive decline and lung function in non-institutionalised older people from the English Longitudinal Study of Ageing (ELSA) in four-year follow-up.
METHODS: Data was collected from the ELSA from the two waves (2004 = 8,688; 2008 = 8,411) a biennial national representative survey, respectively. We carried out lung function test, psychological well-being measured using the Centre for Epidemiologic studies Depression (CESD) and socio-economic data was gathered from a national sample of the non-institutionalised adults aged 50 years or more living in England. Cognitive impairment was assessed using the global cognitive index (GLI) ranged from 0 to 60. We used a repeated measures multivariable mixed linear model to examine the independent effect of COPD on cognitive score adjusting for the effects of covariates.
RESULTS: 6858 adults were included in the study. Fifty-four per cent (n=3686) of the sample were women. The mean GLI score for men versus women (27.7 vs. 28.8, p < 0.0001). GLI was associated with forced expiratory volume in one second (beta 0.31, p< 0.001), younger age (beta = -0.22, p< 0.001), women (beta = 2.07, p < 0.001), CESD (beta = -0.14, p< 0.001), number of friends (beta = 0.14, p < 0.001), daily alcohol consumption (beta= 0.50, p = 0.001) and self-rated health (beta 0.99, p < 0.001) and comorbid stroke (beta -1.17, p< 0.001).
CONCLUSIONS: Older age, male gender, higher depression score, poor self-health reported status, fewer number of friends, comorbid stroke were associated with decline in cognition status. Lower pulmonary function test was associated with lower cognitive performance over time. Further studies are required.
CLINICAL IMPLICATIONS: Physicians and healthcare professionals should be aware of the impact of low lung function and the increased risk for cognitive decline in older people.
DISCLOSURE: The following authors have nothing to disclose: Abebaw Yohannes, Gindo Tampubolon
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