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Huge Bilaterally Cavitary and Nodulary Lung Lesions: Pulmonary Lymphomatoid Granulomatosis FREE TO VIEW

Müesser Parsak, MD; Ismail Hanta, MD
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Çukurova Government Hospital, Adana, Turkey

Chest. 2013;144(4_MeetingAbstracts):948A. doi:10.1378/chest.1701709
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SESSION TITLE: Miscellaneous Global Case Reports

SESSION TYPE: Global Case Report

PRESENTED ON: Tuesday, October 29, 2013 at 01:30 PM - 02:30 PM

INTRODUCTION: Pulmonary lymphomatoid granulomatosis (PLG) is a very rare disorders, characterized by multiple nodular lesions. PLG is considered to be a variant of B-cell lymphoma, associated with Epstein-Barr virus. In this report, we present a case of PLG characterized by multiple large both cavitary, and nodular lesions.

CASE PRESENTATION: Twenty two years old, male patient has admitted to our out-patient clinic with the symptoms of cough, within the last month, and progressive dyspnea, within the last week. Physical and laboratory examination revealed no apparent abnormal findings. There were bilateral multiple great cavities and nodular lesions in his thorax computerized tomography. ANCA was found negative. On fiberoptic bronchoscopy, no pathologic findings were found. Transthoracic fine needle biopsy was, also, negative. Finally, at thoracoscopic biopsy, lymphomatoid granulomatosis was diagnosed histopathologically.

DISCUSSION: PLG, includes a triad, of polymorphic lymphoid infiltrates, transmural infiltration of arteries and veins by lymphoid cells "angiitis", and focal areas of necrosis within the lymphoid infiltrates. The lungs are most commonly involved. The most common radiographic feature is multiple lung nodules, which can be seen in 80% of cases.

CONCLUSIONS: It is thought that PLG should be also considered in the differential diagnosis of multiple cavitary and nodular lesions in the lung.

Reference #1: Roschewski M. Cancer J 2012;18: 469-474.

DISCLOSURE: The following authors have nothing to disclose: Müesser Parsak, Ismail Hanta

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